Evidence map›Paper›PMID 41912124›Full record

ArticleJournal of the American Society of Echocardiography : official publication of the American Society of Echocardiography2026

Adapting Interventional Echocardiography to New Techniques: Echocardiographic Guidance for Transcatheter Myotomy Using Septal Scoring Along the Midline Endocardium.

G Burkhard Mackensen, Ester Canovas-Rodriguez, Richard Sheu, Patrick Gleason, Srdjan Jelacic, Jaffar M Khan, Omar K Khalique, Adam B Greenbaum, Robert J Lederman, Barbara Danek-Karatasakis and 3 more

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In one paragraph

Article in Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

G Burkhard MackensenDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, Washington. Electronic address: gbmac@uw.edu.
Ester Canovas-RodriguezDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, Washington.
Richard SheuDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, Washington.
Patrick GleasonStructural Heart and Valve Center, Emory University Hospital, Atlanta, Georgia.
Srdjan JelacicDepartment of Anesthesiology and Pain Medicine, University of Washington, Seattle, Washington.
Jaffar M KhanDivision of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland; St. Francis Hospital, Roslyn, New York.
Omar K KhaliqueSt. Francis Hospital, Roslyn, New York.
Adam B GreenbaumStructural Heart and Valve Center, Emory University Hospital, Atlanta, Georgia.
Robert J LedermanDivision of Intramural Research, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Barbara Danek-KaratasakisDepartment of Medicine, Division of Cardiology, University of Washington, Seattle, Washington.
Vasilis C BabaliarosStructural Heart and Valve Center, Emory University Hospital, Atlanta, Georgia.
David ElisonDepartment of Medicine, Division of Cardiology, University of Washington, Seattle, Washington.
James M McCabeDepartment of Medicine, Division of Cardiology, University of Washington, Seattle, Washington.

Funding

Novel catheter treatment of valve diseaseZIAHL006040 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI LEDERMAN, ROBERT J · 2010 to 2025
$23.6M
Intramural NIH HHS ZIA HL006040
6 · The paper itself

Abstract

Septal scoring along the midline endocardium (SESAME) is a recently developed electrosurgical, percutaneous myotomy technique. It was designed to prevent iatrogenic left ventricular outflow tract obstruction following transcatheter mitral valve replacement in patients with prohibitive surgical risk. SESAME can also be used to reduce left ventricular outflow tract obstruction in cases of obstructive hypertrophic cardiomyopathy. On the basis of >200 SESAME procedures at three experienced centers, the authors present a best-practices, step-by-step, echocardiography-guided approach, emphasizing key anatomic and procedural features. Given the complexity of the electrosurgical approach, protocol-driven imaging is essential to ensure procedural safety and optimize outcomes.

Indexed as

Cardiac CatheterizationCardiomyopathy, HypertrophicEchocardiographyEndocardiumHeart SeptumSeptal MyectomySurgery, Computer-AssistedUltrasonography, InterventionalVentricular Outflow Obstruction, LeftHumansInterventional echocardiographyLeft ventricular outflow tract obstructionLVOTOSeptal reduction therapiesSESAMETEETranscatheter myotomy

Identifiers

PMID41912124
PMCPMC13355948

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.