Evidence map›Paper›PMID 41912117›Full record

ArticleVirus research2026

Fractional-order modeling of vaccination strategies for measles transmission incorporating immune memory.

Akeem Olarewaju Yunus, Oludolapo Akanni Olanrewaju

Abstract read
In one paragraph

Article in Virus research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Akeem Olarewaju YunusInstitute of Systems Science (ISS), Durban University of Technology, Durban, South Africa. Electronic address: YunusAO@dut.ac.za.
Oludolapo Akanni OlanrewajuInstitute of Systems Science (ISS), Durban University of Technology, Durban, South Africa. Electronic address: OludolapoO@dut.ac.za.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study explores how vaccination, immune memory, and long-term immunity shape the transmission dynamics of measles by developing a fractional-order mathematical model.

methodCaputo-Fabrizio fractional-order SEITR-VL model is formulated, in which population is divided into susceptible, exposed, infectious, treated, recovered, vaccinated, and lifelong immunity classes. The model incorporates memory effects so that past disease and immunity states can influence current transmission behavior. Basic mathematical properties such as positivity, boundedness, and the existence of solutions are verified. The effective reproduction number is derived using the next-generation matrix approach, and numerical solutions are obtained through the Laplace-Adomian Decomposition Method.

resultsNumerical experiments showed that increasing vaccination coverage, as well as improving recovery rates, leads to a clear decline in infection levels. In addition, the fractional-order structure introduces memory effects that moderate sharp epidemic peaks and slow the overall spread of the disease, resulting in smoother outbreak patterns. Since some parameters are not estimated from data, these findings are interpreted mainly at a qualitative level.

conclusionThe results emphasize the importance of vaccination and immune memory in controlling measles transmission. While the fractional-order framework provides a useful way to capture long-term and memory-dependent effects, further validation using real epidemiological data would be necessary for predictive or policy-oriented applications.

Indexed as

Immunologic MemoryMeaslesMeasles VaccineVaccinationDisease OutbreaksHumansModels, TheoreticalMeasles VaccineCaputo–Fabrizio derivativeEpidemiological modelingMeaslesNovel fractional-orderVaccination strategiesVaccine-preventable diseases

Identifiers

PMID41912117
PMCPMC13091136

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.