Evidence map›Paper›PMID 41911246›Full record

ArticlePloS one2026

Evaluation of a training program for rheumatic heart disease screening integrated into the public health system in Uganda.

Paul W Warren, Scott Wirth, Jafesi Pulle, Doreen Nakaagayi, Charles Oyoo Akia, Evelyn Ayaa, Michaela Pardo, Francis Odong, Ronald Ogwanh, John Omagino and 8 more

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Paul W WarrenThe Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.ORCID https://orcid.org/0000-0002-3432-1430
Scott WirthDivision of Pediatric Cardiology, University of Utah School of Medicine, Salt Lake City, Utah, United States of America.
Jafesi PulleUganda Heart Institute, Kampala, Uganda.ORCID https://orcid.org/0000-0001-7955-3481
Doreen NakaagayiUganda Heart Institute, Kampala, Uganda.ORCID https://orcid.org/0000-0003-4010-9951
Charles Oyoo AkiaMinistry of Health, Kampala, Uganda.
Evelyn AyaaKitgum District Health Department, Kampala, Uganda.
Michaela PardoUniversity of Washington, Seattle, Washington, United States of America.
Francis OdongUganda Heart Institute, Kampala, Uganda.
Ronald OgwanhUganda Heart Institute, Kampala, Uganda.
John OmaginoUganda Heart Institute, Kampala, Uganda.
Isaac OtimUganda Heart Institute, Kampala, Uganda.
Craig SableChildren's National Medical Center, Cardiology, Washington, District of Columbia, United States of America.
Alison SpazianiChildren's National Medical Center, Cardiology, Washington, District of Columbia, United States of America.
Henry Okello OttoKitgum District Health Department, Kampala, Uganda.
David WatkinsUniversity of Washington, Seattle, Washington, United States of America.
Emmy OkelloUganda Heart Institute, Kampala, Uganda.
Kristen DanforthUniversity of Washington, Seattle, Washington, United States of America.
Andrea BeatonThe Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, United States of America.

Funding

Accelerating Delivery of rheumatic heart disease preventive iNterventions in Uganda (ADUNU)R01HL164615 · NHLBI · CINCINNATI CHILDRENS HOSP MED CTR · PI Andrea Zawacki Beaton, David A Watkins · 2022 to 2026
$3.0M
NHLBI NIH HHS R01 HL164615
6 · The paper itself

Abstract

introductionEchocardiography screening for rheumatic heart disease (RHD) has gained support as a public health approach, but scale up of RHD screening services is complex. We sought to evaluate the effectiveness of a novel training program to build non-expert competency for RHD echocardiography screening within the Uganda public health system and to describe the human and material resources required to support it.

methodsGuided by a logic model, we evaluated the Accelerating Delivery of Rheumatic Heart Disease Prevention in Northern Uganda (ADUNU) Program, a novel RHD control program, 15 months after its implementation within the Ugandan public health care system.

resultsSixty-one healthcare workers (HCW) across 10 public health facilities started in training under the program, of which 58 (95%) advanced past the initial stage of training and earned conditional certification to screen for RHD with ongoing remote and in-person feedback and oversight. Of these, 17 (29%) completed all stages of training and earned full certification to independently screen for RHD with no ongoing oversight. A total of 17,927 community members were screened through ADUNU during the program's first 15 months. After receiving final certification, 14 HCWs (93%) continued to perform screening echocardiograms (≥20/month) at median follow-up of 8 months [IQR 8-10]. HCW sensitivity and specificity were 61% and 96%, respectively.

conclusionDevelopment and deployment of a large scale RHD screening echocardiography training program within an existing public health system is feasible. Future program iterations are needed to improve HCW screening sensitivity and decrease the reliance on human resources.

Indexed as

Health PersonnelMass ScreeningPublic HealthRheumatic Heart DiseaseAdultEchocardiographyFemaleHumansMaleProgram EvaluationUganda

Identifiers

PMID41911246
PMCPMC13035113

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.