ArticlePloS one2026
Health-related quality of life in children with HIV/AIDS: Child and parent perspectives at a tertiary ART clinic in Kathmandu, Nepal.
Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChildren living with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) face persistent physical, emotional, and social challenges that can reduce their quality of life. In Nepal, evidence describing the health-related quality of life (HRQoL) of this population remains limited.
objectiveTo assess health-related quality of life and the level of agreement between child self-reports and parent proxy reports among children living with HIV/AIDS receiving antiretroviral therapy at a tertiary care hospital in Kathmandu, Nepal.
methodsAn analytical cross-sectional study was conducted from July to September, 2022 among 105 children aged 6-18 years and their parents attending the antiretroviral therapy clinic at Tribhuvan University Teaching Hospital. HRQoL was assessed using the Pediatric Quality of Life Inventory Version 4.0 Generic Core Scales which comprises physical, emotional, social, and school functioning domains, for both child self-reports and parent proxy reports. Descriptive statistics summarized participant characteristics and HRQoL scores. Chi-square and Fisher's exact tests examined associations between sociodemographic variables and quality of life. Intraclass correlation coefficients (ICC) were calculated to assess agreement between child self-reports and parent proxy reports.
resultsMore than half of the children (58.1%) had poor HRQoL. The mean total HRQoL score from child self-reports was 68.8 ± 5.7, with higher scores in the social (73.5 ± 8.1) and physical (73.3 ± 6.1) domains compared to the emotional (65.1 ± 8.9) and school functioning (62.8 ± 7.5) domains. Parent proxy reports showed slightly higher mean scores (70.4 ± 3.7). Overall agreement between child self-reports and parent proxy reports was poor (ICC = 0.405), with the highest agreement observed in the physical functioning domain.
conclusionPoor quality of life is common among children living with HIV/AIDS in Nepal, particularly in emotional and school functioning domains. Targeted interventions addressing psychosocial well-being and educational participation are needed to improve overall quality of life in this group.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.