Evidence map›Paper›PMID 41911085›Full record

ArticlePsychotherapy and psychosomatics2026

A Brief Intervention for the Treatment of Anxiety in Pregnancy: A Pilot Randomized Controlled Trial (The TAP Study).

Sophie Grigoriadis, Neeti Sharma, Cindy-Lee Dennis, Simone N Vigod, Neil Rector, Peggy Richter, Janet Bodley, Karen Fleming, Jon Barret, Alex Kiss and 2 more

Abstract read
In one paragraph

Article in Psychotherapy and psychosomatics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Sophie GrigoriadisDepartment of Psychiatry, Sunnybrook Health Sciences Centre and Sunnybrook Research Institute, Toronto, Ontario, Canada, sophie.grigoriadis@sunnybrook.ca.
Neeti SharmaDepartment of Psychiatry, Sunnybrook Health Sciences Centre and Sunnybrook Research Institute, Toronto, Ontario, Canada.
Cindy-Lee DennisDepartment of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Simone N VigodDepartment of Psychiatry, Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Neil RectorDepartment of Psychiatry, Sunnybrook Health Sciences Centre and Sunnybrook Research Institute, Toronto, Ontario, Canada.
Peggy RichterDepartment of Psychiatry, Sunnybrook Health Sciences Centre and Sunnybrook Research Institute, Toronto, Ontario, Canada.
Janet BodleyDepartment of Obstetrics and Gynecology, Dan Women & Babies Research Program, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada.
Karen FlemingDepartment of Family and Community Medicine, Sunnybrook Health Sciences Center, Toronto, Ontario, Canada.
Jon BarretDepartment of Obstetrics and Gynecology, McMaster University, Hamilton, Ontario, Canada.
Alex KissDepartment of Research Design and Biostatistics, Sunnybrook Research Institute, Toronto, Ontario, Canada.
Anthony LevittDepartment of Psychiatry, Sunnybrook Health Sciences Centre and Sunnybrook Research Institute, Toronto, Ontario, Canada.
Steven SelchenDepartment of Psychiatry, Sunnybrook Health Sciences Centre and Sunnybrook Research Institute, Toronto, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAnxiety during pregnancy affects 1 in 4 pregnancies and is often comorbid with other mental health disorders. Early intervention is crucial to avoid persistent mental health issues and adverse obstetrical, neonatal and child outcomes. Traditional mindfulness-based cognitive therapy is effective, but its uptake is limited by its high resource intensity for patients and healthcare services. This study investigated the feasibility, acceptability, and preliminary efficacy of a novel, brief psychotherapy, "mindful adaptive practice in pregnancy" (MAPP), delivered in a synchronous virtual group format.

methodsThis pilot randomized controlled trial (RCT) was conducted at two university-affiliated health centers. Pregnant persons with elevated anxiety symptoms were randomly assigned to MAPP plus treatment as usual (TAU) or TAU alone. MAPP was delivered in five, 2-h virtual group sessions, over 4 weeks. Feasibility was assessed by recruitment rates and participant eligibility, intervention acceptability through online questionnaires, and adherence by session attendance and follow-up completion. Efficacy was preliminarily evaluated by anxiety symptom change post-treatment.

resultsParticipants were recruited from November 2021 to May 2022, with 69 randomized to MAPP (36 participants) or TAU (33 participants). High acceptability and adherence were reported for MAPP with over 80% attending three or more sessions. Preliminary results suggest significant reduction in anxiety symptoms for participants receiving MAPP compared to TAU.

conclusionMAPP was feasible and well accepted. Preliminary data suggest that this brief, synchronous virtual therapy may effectively reduce anxiety symptoms. Further investigation into MAPP's efficacy in a larger-scale RCT can confirm its viability as an intervention for anxiety during pregnancy.

Indexed as

AnxietyMindfulnessPregnancyPsychotherapyVirtual therapy

Identifiers

PMID41911085
PMCPMC13268614

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.