Evidence map›Paper›PMID 41910861›Full record

Trial reportJournal of clinical monitoring and computing2026

AI-assisted videolaryngoscopy improves intubation success: results from a randomized simulation trial.

Ariadna Comaniciu, David Schurter, Ajsi Kanapari, Giulia Lorenzoni, Asimina Lazaridou, Michael Thomas Ganter, Dario Gregori, Christoph Karl Hofer

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of clinical monitoring and computing, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06657417 (A.I. Supported Laryngoscopy and Endotracheal Intubation), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06657417 nacompletednot on this map

A.I. Supported Laryngoscopy and Endotracheal Intubation: a Manikin Study

TypeinterventionalSponsorSchulthess KlinikRan2024 to 2024Enrolled74ConditionsIntubation, Difficult or FailedArmsVideo laryngoscopy, Video larnygoscopy
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ariadna ComaniciuDivision of Anaesthesia, Schulthess Klinik, Lengghalde 2, 8008, Zürich, Switzerland.ORCID http://orcid.org/0009-0004-4624-2280
David SchurterDivision of Anaesthesia, Schulthess Klinik, Lengghalde 2, 8008, Zürich, Switzerland. david.schurter@kws.ch.ORCID http://orcid.org/0009-0003-0353-5617
Ajsi KanapariUnit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy.ORCID http://orcid.org/0009-0002-5078-6315
Giulia LorenzoniUnit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy.ORCID http://orcid.org/0000-0003-1771-4686
Asimina LazaridouDivision of Anaesthesia, Schulthess Klinik, Lengghalde 2, 8008, Zürich, Switzerland.ORCID http://orcid.org/0000-0002-9203-0009
Michael Thomas GanterInstitute of Anaesthesiology and Intensive Care Medicine, Hirslanden Clinic, Zürich, Switzerland.ORCID http://orcid.org/0000-0003-1234-1833
Dario GregoriUnit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic and Vascular Sciences, University of Padua, Padua, Italy.ORCID http://orcid.org/0000-0001-7906-0580
Christoph Karl HoferDivision of Anaesthesia, Schulthess Klinik, Lengghalde 2, 8008, Zürich, Switzerland.ORCID http://orcid.org/0000-0001-9063-7723

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Video laryngoscopy has become an integral part of today's airway management. Despite its advantages, loss of depth perception and increased cognitive load remain a challenge and not all airway scenarios can be successfully managed and resolved. This study aims to evaluate the efficacy of larynGuide, an AI-based software integrated with the C-MAC video laryngoscope, in improving tracheal intubation success rates. This prospective, randomized, 2 × 2 crossover, simulation-based study included 74 medical professionals, 35 experienced and 39 inexperienced participants. Each participant performed tracheal intubations using a C-MAC video laryngoscope with and without the larynGuide AI overlay in both easy and difficult airway scenarios. The primary outcome was the first attempt success rate. Secondary outcomes included overall success rate, time to intubation, procedural performance scores, and incidence of dental injury. Data were analyzed using mixed effects models with binomial response and non-parametric tests as appropriate. The overall first attempt success rate was 89% with larynGuide and 85% with standard C-MAC, the odds of successful intubation were 72% higher with larynGuide (OR = 1.72, 95%CI = 1.08, 2.73; p = 0.022). Among experienced participants, the benefit was more pronounced (OR = 3.37, 95%CI = 1.2, 8.9; p = 0.016). Time to intubation was longer with larynGuide (median = 29 s) compared to standard C-MAC (median = 23 s, p < 0.01). The incidence of dental damage was lower with larynGuide (22%) compared to C-MAC (27%), although not statistically significant (p = 0.095). The larynGuide AI-powered software improved tracheal intubation success rates compared to standard C-MAC videolaryngoscopy in this simulation-based study, highlighting the potential role of AI in enhancing airway management. Further clinical studies are needed to confirm these results and support broader integration into practice.

trial registrationClinicalTrials.gov ID NCT06657417.

Indexed as

Artificial IntelligenceIntubation, IntratrachealLaryngoscopyAdultAirway ManagementComputer SimulationCross-Over StudiesFemaleHumansLaryngoscopesMaleProspective StudiesSoftwareVideo-Assisted Techniques and ProceduresVideo Recordingairway managementartificial intelligenceC-MAC video laryngoscopelarynGuide softwaresimulation-based studyTracheal intubationvideo laryngoscopy

Identifiers

PMID41910861
PMCPMC13391665

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.