Evidence map›Paper›PMID 41910782›Full record

Trial reportClinical oral investigations2026

Alterations in condylar position and bite force distribution following clear aligner use: a single-arm clinical trial.

Yangruoxuan Liu, Mingbo Wei, Shali Yue, Fang Yang, Hui Xiong

Abstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Yangruoxuan LiuState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, Hubei Province, 430079, China.
Mingbo WeiDepartment of Stomatology, Zhongnan Hospital of Wuhan University, Wuhan, 430071 , China.
Shali YueState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, Hubei Province, 430079, China.
Fang YangState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, Hubei Province, 430079, China.
Hui XiongState Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology, Wuhan University, Wuhan, Hubei Province, 430079, China. xionghui@whu.edu.cn.

Funding

National Key Research and Development Program of China 2023YFC2509200
6 · The paper itself

Abstract

objectivesThis single-arm clinical trial investigated changes in condylar displacement, total of force (TOF), and force distribution during the initial phase of passive clear-aligner wear. MATERIALS AND

methodsThe mandibular condylar displacement (MCD) instrument was employed to measure sagittal, vertical, and horizontal condylar displacement. Simultaneously, the T-Scan system was used to analyze the total of force (TOF), force distribution and occlusal balance. The study comprised twelve healthy adult participants (nine females and three males; mean age: 25.6 years). These individuals consecutively wore two pairs of passive clear aligners for a duration of ten days each. Assessments were conducted on baseline (Day 0), Day 10, and Day 20.

resultsTOF significantly decreased over time (P < 0.05), whereas no notable alterations were observed in other evaluated parameters. In Group CHANGED, TOF markedly decreased on Day 10 and showed partial recovery on Day 20. Statistically significant differences in the anterior/posterior (A/P) bite force ratio between the groups were identified on day 10 and day 20 (P < 0.05). Condylar displacement demonstrated significant increases in both vertical and sagittal dimensions (P < 0.05), predominantly in the distal and downward directions.

conclusionsPassive clear‑aligner wear transiently decreases TOF and occlusal balance during the initial 20 days. The anterior–posterior force ratio may act as a clinical marker for upcoming shifts in mandibular position. Although the average MCD remained stable, some participants exhibited distal‑downward condylar drift. CLINICAL RELEVANCE: Clear aligners have the potential to alter mandibular position downward and distally while somewhat reducing bite forces.

Indexed as

Bite ForceMandibular CondyleOrthodontic Appliances, RemovableAdultFemaleHumansMaleBite forceClear alignerMandibular positionMCDT-Scan

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.