Evidence map›Paper›PMID 41910731›Full record

ArticleNaunyn-Schmiedeberg's archives of pharmacology2026

Buchwald cross-coupling for synthesis of novel N-imidazolyl-N'-aryl ureas and application in bioassay: ADMET profiling, docking and cytotoxicity studies.

Pradeep Kumar Pattanadara Siddappa, Jeevan Chakravarthy Arakalagudu Satyanarayana, Shriraksha Ananthamurthy, Sunil Kumar

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In one paragraph

Article in Naunyn-Schmiedeberg's archives of pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Pradeep Kumar Pattanadara SiddappaDepartment of Chemistry, Sri Siddhartha Institute of Technology, SSAHE, Tumakuru, 572105, India.
Jeevan Chakravarthy Arakalagudu SatyanarayanaDepartment of Chemistry, BMS Institute of Technology & Management, Autonomous under Visvesvaraya Technological University, Bengaluru, Karnataka, 560064, India. jeechakravarthy@gmail.com.
Shriraksha AnanthamurthyDepartment of Biochemistry, Bengaluru City University, Bengaluru, 560001, India.
Sunil KumarDepartment of Chemistry, Sri Siddhartha Institute of Technology, SSAHE, Tumakuru, 572105, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthesis of novel N-imidazolyl-N'-aryl urea via palladium-catalysed Buchwald cross-coupling reaction with substituted aryl halides in the presence of NaOBu

Indexed as

Antineoplastic AgentsImidazolesUreaAnimalsCell Line, TumorCell ProliferationFemaleHumansMolecular Docking SimulationOvarian NeoplasmsStructure-Activity RelationshipAntineoplastic AgentsImidazolesUreaBuchwald–Hartwig cross-coupling reactionMolecular dockingMTT assayOvarian carcinomaTandem two-step synthesis

Identifiers

PMID41910731

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.