Evidence map›Paper›PMID 41910327›Full record

ArticlemBio2026

mGem: Cut4/Apc1 and its prion form at the cross roads of cell cycle regulation, heterochromatin organization, RNAi, stress response, and evolution.

Suman Sharma, Jagmohan Singh

Abstract read
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Suman SharmaAmity University Punjab, Sahibzada Ajit Singh Nagar, Punjab, India.
Jagmohan SinghAmity University Punjab, Sahibzada Ajit Singh Nagar, Punjab, India.ORCID 0000-0003-2775-1245

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anaphase-promoting complex/cyclosome (APC/C) complex plays a pivotal role in cell cycle progression in eukaryotes. APC/C-mediated polyubiquitination and subsequent degradation of regulatory factors ensure sister chromatid separation during mitosis and mitotic exit. Likewise, coordination between the chromodomain protein Swi6/HP1, histone methyltransferase Clr4/Suv39, and RNAi promotes heterochromatin assembly in

Indexed as

Anaphase-Promoting Complex-CyclosomeCell CycleHeterochromatinPrionsRNA InterferenceSchizosaccharomycesSchizosaccharomyces pombe ProteinsStress, PhysiologicalCell Cycle ProteinsAnaphase-Promoting Complex-CyclosomeCell Cycle ProteinsHeterochromatinPrionsSchizosaccharomyces pombe Proteinsanaphase-promoting complexepigeneticsheterochromatinprionsRNA interferencestress resppnse

Identifiers

PMID41910327
PMCPMC13170268

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.