Evidence map›Paper›PMID 41910261›Full record

ArticleMicrobiology spectrum2026

Role of STAT1 in modulating the host immune response to

Yifan Sun, Chenyan Du, Qinwen Xu, Zhe Chen, Xin Feng, Su Han, Yan Yan, Bo Wang, Zhiyue Lv, Guoding Zhu and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yifan Sun *Laboratory of Pathogen Infection and Immunity, Department of Public Health and Preventive Medicine, Jiangnan University, Wuxi School of Medicine, , Wuxi, Jiangsu, China.ORCID 0009-0004-4128-2371
Chenyan Du *Laboratory of Pathogen Infection and Immunity, Department of Public Health and Preventive Medicine, Jiangnan University, Wuxi School of Medicine, , Wuxi, Jiangsu, China.
Qinwen Xu *Laboratory of Pathogen Infection and Immunity, Department of Public Health and Preventive Medicine, Jiangnan University, Wuxi School of Medicine, , Wuxi, Jiangsu, China.
Zhe ChenLaboratory of Pathogen Infection and Immunity, Department of Public Health and Preventive Medicine, Jiangnan University, Wuxi School of Medicine, , Wuxi, Jiangsu, China.
Xin FengLaboratory of Pathogen Infection and Immunity, Department of Public Health and Preventive Medicine, Jiangnan University, Wuxi School of Medicine, , Wuxi, Jiangsu, China.
Su HanLaboratory of Pathogen Infection and Immunity, Department of Public Health and Preventive Medicine, Jiangnan University, Wuxi School of Medicine, , Wuxi, Jiangsu, China.
Yan YanLaboratory for Infection and Immunity, Affiliated Hospital of Jiangnan University, The Fifth People's Hospital of Wuxi, Wuxi, Jiangsu, China.
Bo WangDepartment of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, China.
Zhiyue LvZhongshan School of Medicine, Sun Yat-sen University, Guangzhou, Guangdong, China.
Guoding ZhuKey Laboratory of National Health and Family Planning Commission on Parasitic Disease Control and Prevention, Jiangsu Provincial Key Laboratory on Parasite and Vector Control Technology, Jiangsu Institute of Parasite Diseases, Wuxi, Jiangsu, China.
Jianping CaoNational Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention (Chinese Center for Tropical Diseases Research), NHC Key Laboratory of Parasite and Vector Biology, WHO Collaborating Centre for Tropical Diseases, National Center for International Research on Tropical Diseases, Shanghai, China.ORCID 0000-0002-1974-0047
Yang ChengLaboratory of Pathogen Infection and Immunity, Department of Public Health and Preventive Medicine, Jiangnan University, Wuxi School of Medicine, , Wuxi, Jiangsu, China.ORCID 0000-0002-3014-342X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The spleen is critically involved in the immune response to malaria parasite infections. However, the precise molecular mechanisms underlying splenic immune regulation and anemia during malaria remain elusive. This study aimed to identify the key regulatory proteins in

Indexed as

anemiaCD8+T cellIFN-γMalariaPlasmodium yoeliiSTAT1

Identifiers

PMID41910261
PMCPMC13142038

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.