Evidence map›Paper›PMID 41910094›Full record

ArticleHuman vaccines & immunotherapeutics2026

DTaP-induced infantile epileptic spasms syndrome high-risk window: Insights from school-age children.

Qi Zhang, Wen He, Meng-Na Zhang, Lin-Yan Hu, Xiu-Yu Shi, Yang-Yang Wang, Qian Lu, Qiu-Hong Wang, Li-Ying Liu, Hai-Qing Zhao and 6 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Human vaccines & immunotherapeutics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Qi ZhangMedical School of Chinese PLA, Beijing, China.
Wen HeSenior Department of Pediatrics, Chinese PLA General Hospital, Beijing, China.
Meng-Na ZhangMolecular Diagnosis Center, The Affiliated Hospital of Chengde Medical University, Hebei, China.
Lin-Yan HuSenior Department of Pediatrics, Chinese PLA General Hospital, Beijing, China.
Xiu-Yu ShiSenior Department of Pediatrics, Chinese PLA General Hospital, Beijing, China.
Yang-Yang WangSenior Department of Pediatrics, Chinese PLA General Hospital, Beijing, China.
Qian LuDepartment of Pediatrics, First Hospital of Qinhuangdao, Hebei, China.
Qiu-Hong WangDepartment of Neurology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Li-Ying LiuDepartment of Pediatrics, Xuanwu Hospital, Capital Medical University, Beijing, China.
Hai-Qing ZhaoSenior Department of Pediatrics, Chinese PLA General Hospital, Beijing, China.
Jia WangMedical School of Chinese PLA, Beijing, China.
Jiu-Wei LiDepartment of Neurology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Jian-Bo ZhaoDepartment of Neurology, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.
Ying ZhangDepartment of Pediatrics, The Affiliated Hospital of Qingdao University, Qingdao, China.
Jing WangSenior Department of Pediatrics, Chinese PLA General Hospital, Beijing, China.
Li-Ping ZouSenior Department of Pediatrics, Chinese PLA General Hospital, Beijing, China.ORCID 0000-0001-7233-9378

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To determine the specific high-risk characteristics and temporal window associated with Diphtheria, Tetanus, and acellular Pertussis (DTaP) vaccine-precipitated infantile epileptic spasms syndrome (IESS), providing evidence for optimizing vaccination safety strategies, we conducted a multicenter retrospective cohort study of 564 patients with long-term follow-up (6.5-10.5 y). Patients were stratified by seizure onset interval into Vaccination-proximate (≤72 hours) and distant (>72 hours) groups. The proximate group (n = 53, 9.4%) exhibited a significantly younger age distribution (median [IQR]: 5.0 [3.0-6.0] vs. 5.0 [4.0-7.0] months,

Indexed as

Diphtheria-Tetanus-acellular Pertussis VaccinesSpasms, InfantileChildChild, PreschoolFemaleFollow-Up StudiesHumansInfantMaleRetrospective StudiesDiphtheria-Tetanus-acellular Pertussis VaccinesDiphtheria, Tetanus, and acellular Pertussis (DTaP) vaccinedose-specific riskInfantile epileptic spasms syndromeprecipitating factorvaccinationvaccine safety

Identifiers

PMID41910094
PMCPMC13037439

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