Evidence map›Paper›PMID 41910053›Full record

ArticleJournal of water and health2026

A dual-branch deep learning framework for tiered early warning of COVID-19 utilizing wastewater data.

Xiaoqiang Li, Changqian Wu, Jingyi Jiang, Shufan Wu, Cheng Zhu, Minhui Yang, Zhiyong Chen, Xiaoyue Chen, Lifeng Tan

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of water and health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaoqiang LiChangzhou Center for Disease Control and Prevention, Changzhou, Jiangsu 213022, China.ORCID https://orcid.org/0000-0001-6845-2896
Changqian WuChangzhou Center for Disease Control and Prevention, Changzhou, Jiangsu 213022, China.
Jingyi JiangChangzhou Center for Disease Control and Prevention, Changzhou, Jiangsu 213022, China.
Shufan WuChangzhou Center for Disease Control and Prevention, Changzhou, Jiangsu 213022, China.
Cheng ZhuChangzhou Sewage Treatment Co., Ltd, Changzhou, Jiangsu 213031, China.
Minhui YangChangzhou Sewage Treatment Co., Ltd, Changzhou, Jiangsu 213031, China.
Zhiyong ChenChangzhou Center for Disease Control and Prevention, Changzhou, Jiangsu 213022, China.
Xiaoyue ChenChangzhou Center for Disease Control and Prevention, Changzhou, Jiangsu 213022, China.
Lifeng TanChangzhou Center for Disease Control and Prevention, Changzhou, Jiangsu 213022, China.

Funding

Changzhou Science and Technology Project CJ20245051Open Research Fund Program of Changzhou Institute for Advanced Study of Public Health, Nanjing Medical University CPHN202302
6 · The paper itself

Abstract

backgroundWastewater offers earlier, population-level signals, yet few models integrate environmental drivers for reliable routine COVID-19 alerts. We hypothesized that combining wastewater and environmental covariates in a dual-branch deep model leveraging FFT would improve forecasting and alerting.

methodsUsing weekly wastewater, meteorological, and case data from Changzhou, China (Jan 29-Dec 10, 2024), we developed a framework that forecasts case trajectories and triggers tiered yellow/red alerts at predefined thresholds.

resultsOn 2-week-ahead internal tests, performance was: RMSE 1.40 (1.13-1.67), MAE 1.23 (0.99-1.48), MAPE 10.44% (5.20-16.40), and

conclusionsThe novel framework delivers accurate, timely forecasts and reliable early warnings from multi-source data, supporting proactive public health response to COVID-19. It may also be a promising approach for the prediction of other infectious diseases. However, validating and adapting the approach across locations, and epidemic patterns is a key next step to establish robustness, generalizability, and operational value.

Indexed as

COVID-19Deep LearningWastewaterChinaForecastingHumansPandemicsPredictive Learning ModelsSARS-CoV-2WastewaterCOVID-19deep learningearly warningsewagesurveillancewasted water

Identifiers

PMID41910053

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.