Evidence map›Paper›PMID 41909908›Full record

ArticleGut microbes reports2025

Synbiotic combination of

Riko Mishima, Ryuta Ejima, Satoshi Arai, Ayako Horigome, Eri Mitsuyama, Hiroki Kaneko, Kana Yamaguchi, Keita Kamezaki, Yuka Togashi, Kiyoshi Nakamura and 5 more

Abstract read
In one paragraph

Article in Gut microbes reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Trial
  2. Microorganisms · 2026
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Riko MishimaInnovative Research Institute, Morinaga Milk Industry Co., Ltd., Zama, Kanagawa, Japan.ORCID https://orcid.org/0000-0003-0961-1628
Ryuta EjimaInnovative Research Institute, Morinaga Milk Industry Co., Ltd., Zama, Kanagawa, Japan.ORCID https://orcid.org/0009-0008-1658-3470
Satoshi AraiInnovative Research Institute, Morinaga Milk Industry Co., Ltd., Zama, Kanagawa, Japan.ORCID https://orcid.org/0000-0002-0700-6830
Ayako HorigomeInnovative Research Institute, Morinaga Milk Industry Co., Ltd., Zama, Kanagawa, Japan.
Eri MitsuyamaInnovative Research Institute, Morinaga Milk Industry Co., Ltd., Zama, Kanagawa, Japan.
Hiroki KanekoInnovative Research Institute, Morinaga Milk Industry Co., Ltd., Zama, Kanagawa, Japan.ORCID https://orcid.org/0009-0003-7337-9496
Kana YamaguchiInnovative Research Institute, Morinaga Milk Industry Co., Ltd., Zama, Kanagawa, Japan.
Keita KamezakiMetagen, Inc., Tsuruoka, Yamagata, Japan.
Yuka TogashiMetagen, Inc., Tsuruoka, Yamagata, Japan.
Kiyoshi NakamuraMedical Corporation Hiroaki Kunitachi Sakura Hospital, Kunitachi, Tokyo, Japan.
Noriyuki IwabuchiInnovative Research Institute, Morinaga Milk Industry Co., Ltd., Zama, Kanagawa, Japan.
Miyuki TanakaInnovative Research Institute, Morinaga Milk Industry Co., Ltd., Zama, Kanagawa, Japan.
Toshitaka OdamakiInnovative Research Institute, Morinaga Milk Industry Co., Ltd., Zama, Kanagawa, Japan.ORCID https://orcid.org/0000-0001-6019-9240
Shinji FukudaMetagen, Inc., Tsuruoka, Yamagata, Japan.ORCID https://orcid.org/0000-0001-5161-9880
Yuji NaitoDepartment of Human Immunology and Nutrition Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.ORCID https://orcid.org/0000-0001-5443-788X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut microbiota and their metabolites are crucial for metabolic regulation, immunomodulation, and brain and mental functions via the brain-gut axis. Synbiotics offer an effective strategy for improving gut health by modulating gut microbiota, leading to improved physical and mental health. In the present study, an exploratory investigation into the effects of synbiotic yogurt on physical and mental health was conducted. Healthy adults consumed fermented milk containing

Indexed as

aromatic lactic acidsgut microbiotapresenteeismQOLSynbiotics

Identifiers

PMID41909908
PMCPMC12940110

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.