ArticleFrontiers in cellular and infection microbiology2026
Multifactorial impacts of blood culture process optimization on clinical outcomes and healthcare economics in bloodstream infection management.
Article in Frontiers in cellular and infection microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To investigate the clinical and health economic impacts of individual workflow components. The effects of phased process optimizations were quantified using empirical data. Methods: From August 2023 to October 2024, the outcomes before and after workflow optimization were compared. The control group comprised patients processed under conventional protocols, while the experimental group included those managed with optimized workflows. Results: Phase I revealed significant temporal reductions through MALDI-TOF enhanced biofilm identification. The Gram-stain reporting time decreased from 33.3 h to 25.7 h ( Conclusion: Quantitative analysis of these optimizations elucidated their differential impacts on blood culture workflows and prognostic determinants. These findings advocate for laboratory innovation as a driver of antimicrobial stewardship and precision medicine for management of microbial bloodstream infections.
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