ArticleFrontiers in bioinformatics2026
Population HLA coverage of experimentally characterized
Article in Frontiers in bioinformatics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Objective: Malaria remains a significant global health challenge, with Methodology: Sixteen experimentally validated CD8 Result: CSPep1, CSPep2, CSPep4, CSPep6, CSPep9, CSPep10, CSPep11, and TRAPep1 were 100% conserved across the sixteen strains of Conclusion: These findings highlight the importance of integrating host HLA binding promiscuity and parasite epitope conservation in developing universal or pan multi-epitope malaria vaccines. By combining conserved epitopes with broad HLA coverage, this approach promotes wide immune recognition while limiting strain-specific immune evasion. Incorporating relevant HLA class II and antibody epitopes could further enhance immune responses, providing effective protection for both children in malaria-endemic regions and malaria-naïve travelers.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.