ArticleClinical, cosmetic and investigational dermatology2026
Analysis and Comparison of the Trends in Burden of Acne Vulgaris in China and Worldwide from 1990 to 2021.
Article in Clinical, cosmetic and investigational dermatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Acne vulgaris is a common chronic inflammatory skin disease with substantial psychosocial consequences, primarily affecting adolescents. Despite its global prevalence and significant impact on quality of life, long-term and standardized comparisons of acne burden between China and the rest of the world remain limited. This study aimed to analyze and compare trends in the burden of acne vulgaris in China and worldwide from 1990 to 2021, with a particular focus on sex- and age-specific differences. Methods: Data were extracted from the Global Burden of Disease 2021 study. Incidence, prevalence, and disability-adjusted life years were assessed. Age-standardized rates were calculated, and trends quantified using average annual percentage change and Joinpoint regression. Results: Globally, acne burden increased, with age-standardized incidence rising from 1442.92 to 1645.24 per 100,000. In China, absolute cases declined, but standardized rates increased. Adolescents aged 10-19 years consistently showed the highest burden, with females more affected. China exhibited earlier and faster increases in standardized rates compared to global trends. Conclusion: The acne burden has increased over the past three decades, especially among adolescents and females, highlighting the need for targeted prevention and management strategies.
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