ReviewBioactive materials2026
Marine collagen for regenerative medicine: Structure-function advantages, limitations, and translational pathways.
Review in Bioactive materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Collagen Scaffolds in Veterinary Medicine: Safety, Sustainability, and Clinical Accessibility of Mammalian- and Marine-Derived Sources-A Scoping Review.Animals : an open access journal from MDPI · 2026Review
- Methacrylation of Fibrillar Sea Urchin Collagen: Production of Sustainable, Stable, and Functional Hydrogels.ACS omega · 2026Article
- Sulfated Polysaccharides in Wound Healing: From Bioactive Materials Design to Regenerative Therapeutics.International journal of nanomedicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Marine collagen is emerging as a transformative natural-derived material in regenerative medicine. Unlike traditional mammalian collagen, it has unique structural properties (e.g., a distinct amino acid profile) that confer high biocompatibility and low immunogenicity, along with excellent antibacterial activity and a sustainable supply chain that eliminates zoonotic disease risks. This review establishes the foundational rationale for this shift by conducting a comprehensive analysis of the structure-function relationships underpinning the regenerative superiority of marine collagen. We critically evaluate how advanced manufacturing technologies (e.g., 3D bioprinting, electrospinning) leverage these intrinsic properties to deliver transformative therapeutic outcomes, exemplified by biomechanically optimized cartilage scaffolds and immunomodulatory wound matrices. Our review also delineates actionable pathways for clinical translation, addressing challenges in scalability, regulatory compliance, and long-term stability. This review uniquely integrates structure-function relationships with green industrialization pathways, offering an actionable framework for clinical translation of marine collagen, which repositions marine collagen from a mere alternative to an indispensable platform material, poised to drive the next generation of regenerative therapies.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.