ArticleCureus2026
Atypical Parkinsonism as a Manifestation of Central Nervous System Lymphoma.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary central nervous system (CNS) lymphoma is an uncommon form of non-Hodgkin lymphoma with a wide range of presentations that can mimic various neurological diseases, including neurodegenerative disorders. We report the case of a 74-year-old man admitted with a seven-month history of progressive cognitive decline and gait disturbances. On examination, he presented cognitive dysfunction, impaired ocular movements, right-predominant parkinsonism, and postural instability. Initial investigations, including imaging studies, electroencephalography, cerebrospinal fluid analysis, and laboratory tests, did not reveal relevant abnormalities, leading to a working diagnosis of probable progressive supranuclear palsy. The patient's condition continued to worsen, and a repeat MRI was performed, revealing findings suggestive of lymphoma. A biopsy confirmed the diagnosis, and corticosteroid therapy was initiated. The patient was subsequently referred to hematology. Although parkinsonism is rarely an initial manifestation of primary CNS lymphoma, the duration and rapid progression of symptoms warranted inpatient investigation, enabling the correct diagnosis and timely initiation of treatment of a potentially curable malignancy.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.