ArticleCureus2026
Predictors of Positive Axillary Node Clearance Following Positive Sentinel Node Biopsy: A Retrospective Analysis.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Axillary management in breast cancer is increasingly de-escalated. This study assessed whether sentinel node biopsy (SNB) histological features predict further axillary disease. Methods A retrospective single-centre study was performed of patients with primary breast cancer who underwent axillary node clearance (ANC) following a positive SNB. Sentinel node deposit size and extracapsular spread were analysed using t-tests and chi-square testing. Logistic regression with receiver operating characteristic analysis was used to evaluate deposit size as a predictor of positive ANC. Results Forty-two patients were included, of whom 23 (55%) had further nodal metastases. Larger SN deposits were associated with positive ANC (p=0.020). Logistic regression identified deposits <3 mm as predictive of no further axillary disease. Extracapsular spread was also significant (p=0.042). Conclusions These findings support selective axillary de-escalation, although validation in larger prospective studies is required.
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