ArticleCureus2026
Facial Paralysis Associated With Lyme Neuroborreliosis in Pediatric Patients: A Multicenter Retrospective Study in Eastern France From 2014-2020.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionLyme neuroborreliosis (LNB) is a recognized cause of peripheral facial paralysis (PFP) in children, particularly in endemic regions. Differentiating LNB from idiopathic facial paralysis at initial presentation remains challenging, as early biological confirmation may be delayed. This study aimed to determine the proportion of LNB among children presenting with facial paralysis at two tertiary pediatric centers in Eastern France, to identify clinical, epidemiological, and biological characteristics associated with LNB, and to evaluate local diagnostic and therapeutic practices in order to propose an updated management algorithm.
methodsWe conducted a multicenter retrospective study including patients under 18 years of age presenting with facial paralysis at the pediatric hospitals of Nancy (January 2014 to December 2018) and Reims (January 2014 to December 2020), France. Patients were identified using ICD-10 codes and classified according to final diagnosis. Demographic, epidemiological, clinical, biological, and therapeutic data were extracted from electronic medical records. Comparative analyses were performed to identify characteristics associated with LNB and to evaluate diagnostic and treatment practices.
resultsAmong 159 children with facial paralysis, 18 (11.3%) were diagnosed with LNB. Clinical features more frequently observed in LNB included general symptoms (44.4% vs. 15.6%, p<0.05) and associated neurological signs (44.4% vs. 22%, p<0.05). Tick bite history and erythema migrans were infrequently reported. Biological findings such as positive Borrelia serology and cerebrospinal fluid lymphocytic pleocytosis were observed in patients with LNB and contributed to diagnostic confirmation. Complete recovery rates did not differ significantly between groups.
conclusionIn this endemic region, LNB accounted for a substantial proportion of pediatric facial paralysis cases. Early clinical features, particularly general and neurological symptoms, may help guide diagnostic evaluation before biological confirmation. These findings support the development of a structured management algorithm adapted to endemic settings to improve diagnostic accuracy and optimize patient care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.