ArticleCureus2026
Neuraxial-Enhanced Hemodynamic Control in a Nine-Year-Old Child With Pheochromocytoma: A Case Report.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pheochromocytoma is a rare cause of severe secondary hypertension in children, and its perioperative management can be particularly challenging due to catecholamine-mediated hemodynamic instability. We report a case of a nine-year-old male with glucose-6-phosphate dehydrogenase (G6PD) deficiency who presented with blurred vision and papilledema and was found to have a systolic blood pressure of 190 mmHg, consistent with a hypertensive emergency. Imaging revealed a 5.2 × 3.5 × 5.5 cm vascular left adrenal mass with central necrosis, and biochemical testing showed markedly elevated urinary vanillylmandelic acid and normetanephrines, confirming the diagnosis of adrenal pheochromocytoma. Echocardiography demonstrated mild to moderate concentric left ventricular hypertrophy. Preoperative optimization included titrated alpha-adrenergic blockade with prazosin, sequential beta-blockade, and intravascular volume expansion. The anesthetic approach combined general anesthesia with a neuraxial enhanced technique, using intrathecal dexmedetomidine and morphine for sympatholysis, along with magnesium sulfate (50 mg·kg⁻¹) as a catecholamine-suppressing adjunct. Intraoperatively, only brief episodes of hypertension were observed, and these were effectively controlled with small boluses of labetalol and esmolol, without the need for continuous vasoactive infusions. Hemodynamics stabilized promptly after adrenal vein ligation. The postoperative course was uneventful. This report suggests that neuraxial enhanced multimodal sympatholytic strategies may facilitate stable perioperative hemodynamic control in pediatric pheochromocytoma.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.