ArticleCureus2026
Racial and Gender Disparities in the Occurrence and Outcomes of Alcohol-Associated Hepatitis in Hospitalized Patients With Prior Bariatric Surgery.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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8 authors.
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Abstract
Background There is an increased risk of alcohol use disorder post-bariatric surgery. The impact of bariatric surgery on the outcomes of alcohol-associated hepatitis (AAH) remains unclear. Hence, we aimed to evaluate whether a history of bariatric surgery influences in-hospital outcomes of AAH and whether these associations vary by sex or race. Methodology We conducted a retrospective, cross-sectional study using the 2016-2020 National Inpatient Sample to identify adult hospitalizations with AAH and bariatric surgery diagnoses. We performed a 1:1 propensity score matching. Matching variables included baseline characteristics (age, sex, primary payer source, race, etc.), clinical comorbidities (diabetes, hypertension, etc.), and outcomes (in-hospital mortality, acute kidney injury, heart failure, major adverse cardiovascular event, length of stay, death, etc). Multivariable regression was performed to compare in-hospital mortality, hepatic decompensation, and other complications. Subgroup analyses were used to assess disparities by sex and race. Results Among 100,910 AAH admissions, 2.3% had a history of bariatric surgery. After matching, bariatric surgery was associated with significantly lower odds of in-hospital mortality (adjusted odds ratio (aOR) = 0.55, 95% confidence interval (CI) = 0.35-0.89), hepatic decompensation (aOR = 0.58, 95% CI = 0.44-0.77), acute kidney injury (aOR = 0.72, 95% CI = 0.60-0.87), and acute respiratory distress syndrome (aOR = 0.64, 95% CI = 0.46-0.91). Female and Black patients had statistically higher likelihood of AAH hospitalization following bariatric surgery compared to males (aOR = 6.90, 95% CI = 6.15-7.74) and White patients (aOR = 1.18, 95% CI = 1.04-1.35), respectively. No differences in outcomes were observed across sex or race. Conclusions Among AAH patients, prior bariatric surgery was associated with significantly improved in-hospital outcomes and may suggest a potential protective effect of metabolic optimization.
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