Evidence map›Paper›PMID 41909220›Full record

ArticleCancer management and research2026

Development and Validation of a Nomogram for Predicting Postoperative Deep Vein Thrombosis Risk in Patients After Laparoscopic Partial Nephrectomy.

Chunyan Wu, Yujia Li, Xianglian Wang, Hanlin Pan, Duoyun Jiang

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Article in Cancer management and research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Chunyan WuSchool of Nursing, Yongzhou Vocational Technical College, Yongzhou, Hunan, 425100, People's Republic of China.
Yujia LiDepartment of Urinary Surgery, The Central Hospital of Yongzhou, Yongzhou, Hunan, 425000, People's Republic of China.
Xianglian WangDepartment of Urinary Surgery, The Central Hospital of Yongzhou, Yongzhou, Hunan, 425000, People's Republic of China.
Hanlin PanSchool of Nursing, Yongzhou Vocational Technical College, Yongzhou, Hunan, 425100, People's Republic of China.
Duoyun JiangDepartment of Urinary Surgery, The Central Hospital of Yongzhou, Yongzhou, Hunan, 425000, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To construct a nomogram model for individualized prediction of risk of deep vein thrombosis (DVT) in renal cell carcinoma (RCC) patients after laparoscopic partial nephrectomy (PN). Methods: A retrospective study was conducted on 556 RCC patients admitted to our hospital from January 2015 to January 2025. Patients were randomly divided into a modeling group (n=389) and a validation group (n=167) at a ratio of 7:3. The modeling group was further subdivided into DVT and non-DVT groups based on postoperative DVT occurrence. Clinical data were collected. Logistic regression was used to analyze the influencing factors. R software was used to construct the nomogram. ROC curves were generated to evaluate the discrimination ability of the nomogram. Decision curve analysis (DCA) was performed to assess its clinical utility. Results: Of 556 patients, 100 (17.98%) developed DVT, including 70 (17.99%) in the modeling group. Logistic regression identified age, operation time, time in bed, pneumoperitoneum pressure, duration of indwelling drains, total cholesterol (TC), and D-dimer as significant risk factors (P < 0.05). The area under the curve (AUC) was 0.889 for the modeling group and 0.866 for the validation group. Hosmer-Lemeshow test indicated good calibration (modeling group: χ²=7.120, P=0.714; validation group: χ²=7.058, P=0.724). DCA showed clinical utility for predicted probabilities between 0.08 and 0.96. Conclusion: Age, operation time, time in bed, pneumoperitoneum pressure, duration of indwelling drains, TC, and D-dimer are risk factors for DVT in patients after laparoscopic PN. The constructed nomogram demonstrates good predictive performance and can be used for individualized risk assessment of postoperative DVT in RCC patients.

Indexed as

deep vein thrombosisnomogrampartial nephrectomyrenal cell carcinomarisk factors

Identifiers

PMID41909220
PMCPMC13021382

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