A rapid and reliable strategy for identification of LNP and protein corona in vitro and in vivo.

Rui Wang, Hui Wang, Ting Li, Guanghui Zi, Zhenyu Yang, Yuhong Xu, Baowei Peng

Abstract read

In one paragraph

Article in International journal of pharmaceutics: X, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Assembly of Multilevel Nanoconstructs with Negatively Charged Lipid Envelope and Features of Its Interaction with Protein Corona.Nanomaterials (Basel, Switzerland) · 2026
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rui WangCollege of Pharmacy, DaLi University, No. 2 Hongsheng Road, Dali City, Yunnan Province 671000, China.

Hui WangCollege of Pharmacy, DaLi University, No. 2 Hongsheng Road, Dali City, Yunnan Province 671000, China.

Ting LiCollege of Pharmacy, DaLi University, No. 2 Hongsheng Road, Dali City, Yunnan Province 671000, China.

Guanghui ZiCollege of Pharmacy, DaLi University, No. 2 Hongsheng Road, Dali City, Yunnan Province 671000, China.

Zhenyu YangCollege of Pharmacy, DaLi University, No. 2 Hongsheng Road, Dali City, Yunnan Province 671000, China.

Yuhong XuCollege of Pharmacy, DaLi University, No. 2 Hongsheng Road, Dali City, Yunnan Province 671000, China.

Baowei PengCollege of Pharmacy, DaLi University, No. 2 Hongsheng Road, Dali City, Yunnan Province 671000, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study develops an integrated analytical method for visual verification and subsequent analysis of lipids and protein coronas of lipid nanoparticles (LNPs) in vitro and in vivo. In this strategy, SDS-PAGE combined with Coomassie brilliant blue (CBB) staining enabled rapid and reliable visual verification and semi-quantification of LNPs/lipids in solutions, yielding a linear standard curve of R

Indexed as

Coomassie brilliant blueLipid nanoparticleMass spectrometrySDS-PAGESize exclusion chromatographySucrose density gradient centrifugation

Identifiers

PMID41909168

DOI10.1016/j.ijpx.2026.100519

PMCPMC13018965

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.