Evidence map›Paper›PMID 41909057›Full record

ReviewFrontiers in digital health2026

Virtual reality in treatment of psychological disorders: a systematic review.

Jihane Ghorayeb, Rupa Kalahasthi, Niki Hosseini-Kamkar

Abstract readReview
In one paragraph

Review in Frontiers in digital health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jihane GhorayebDepartment of Liberal Arts, Rochester Institute of Technology-Dubai, Dubai, United Arab Emirates.
Rupa KalahasthiDepartment of Liberal Arts, Rochester Institute of Technology-Dubai, Dubai, United Arab Emirates.
Niki Hosseini-KamkarDepartment of Liberal Arts, Rochester Institute of Technology-Dubai, Dubai, United Arab Emirates.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The paper aims to systematically review the literature on the efficacy of virtual reality (VR) based therapies to treat mental health disorders in Randomized Control Trials (RCTs). Methods: As of January 2,025, three databases were searched using relevant key terms (PsycINFO, PubMed, and Medline) and Rayyan tool. Eligible studies were English-language RCTs of VR-based interventions with a clearly specified therapeutic framework (e.g., CBT) in adult psychiatric populations. We excluded pediatric or neurodevelopmental samples, animal studies, psychiatric symptoms secondary to medical conditions and those using non-immersive VR (e.g., AR) or inadequately described interventions. The three authors screened the abstracts and rotated the full review of selected papers. From the 1611 papers generated from the search results 41 were included in the systematic review, encompassing anxiety, mood, trauma-related, obsessive-compulsive, eating, substance use, and psychotic disorders. Results: Narrative syntheses of RCTs studies showed that across diagnostic categories, VR-based therapies outperformed waitlist and other inactive controls. For specific phobias, panic disorder with agoraphobia, and social anxiety, VR exposure was generally as effective as Conclusion: Overall, results support VR as an effective therapeutic modality, though heterogeneity across findings limits conclusions about its superiority over established evidence-based

Indexed as

mental health illnessespsychological disorderrandomized control trialssystematic reviewvirtual reality therapy

Identifiers

PMID41909057
PMCPMC13017851

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.