Evidence map›Paper›PMID 41908666›Full record

ArticleCancer pathogenesis and therapy2026

Rare internal malignancies in xeroderma pigmentosum: A report of two cases from Tunisia and analysis of driver mutations.

Soumaya Rammeh, Yasmine Ben Taher, Mariem Ben Rekaya, Sarra Ben Rejeb, Ahlem Lahmar, Meriem Jones, Faten Zeglaoui, Neila Belguith

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancer pathogenesis and therapy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Soumaya RammehFaculty of Medicine of Tunis, LR23ES02, University Tunis El Manar, Tunis 1007, Tunisia.
Yasmine Ben TaherFaculty of Medicine of Tunis, LR23ES02, University Tunis El Manar, Tunis 1007, Tunisia.
Mariem Ben RekayaFaculty of Medicine of Tunis, LR23ES02, University Tunis El Manar, Tunis 1007, Tunisia.
Sarra Ben RejebPathology Department, Security Forces Hospital, La Marsa 2078, Tunisia.
Ahlem LahmarDepartment of Pathology, Mongi Slim Hospital, La Marsa 2070, Tunisia.
Meriem JonesDepartment of Dermatology, Charles Nicolle Hospital, Tunis 1006, Tunisia.
Faten ZeglaouiDepartment of Dermatology, Charles Nicolle Hospital, Tunis 1006, Tunisia.
Neila BelguithLaboratory of Human Molecular Genetics, Medical School of Sfax, University of Sfax, Sfax 3029, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Xeroderma pigmentosum (XP)-associated internal malignancies are characterized by their rarity, early onset, atypical histological presentations, and poorly characterized genomic landscape. In this study, we report the clinical, pathological, and molecular features of two rare XP-associated internal malignancies, focusing on their somatic mutation profiles. These tumors represented rare histological variants at their respective anatomical sites: an ovarian high-grade sex cord-stromal tumor (HG-SCST) with heterologous rhabdomyosarcomatous differentiation diagnosed in an 18-year-old female, harboring a homozygous XP Complementation Group C (

Indexed as

High-throughput nucleotide sequencingNeoplasmsSomatic mutationXeroderma pigmentosum

Identifiers

PMID41908666
PMCPMC13022642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.