Evidence map›Paper›PMID 41908592›Full record

ArticleInfection and drug resistance2026

A Clinical Assessment of the Safety and Efficacy of VELVERT

Sudhir Kumar, Suvash Sahu, Shivam Sharma, Srishti Bhatt, Shikhar Agarwal, Amit Singh

Abstract read
In one paragraph

Article in Infection and drug resistance, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sudhir KumarDepartment of Plastic Surgery, MLB Medical College, Jhansi, Uttar Pradesh, India.
Suvash SahuDepartment of Dermatology, MLB Medical College, Jhansi, Uttar Pradesh, India.
Shivam SharmaDepartment of Surgery, MLB Medical College, Jhansi, Uttar Pradesh, India.ORCID 0009-0003-8013-7866
Srishti BhattDepartment of Surgery, MLB Medical College, Jhansi, Uttar Pradesh, India.
Shikhar AgarwalDepartment of Surgery, MLB Medical College, Jhansi, Uttar Pradesh, India.
Amit SinghDepartment of Surgery, MLB Medical College, Jhansi, Uttar Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Necrotizing fasciitis (NF), a severe form of Necrotizing Soft Tissue Infection (NSTI), is a rapidly progressing, life-threatening condition characterized by extensive tissue destruction. Standard management involves early surgical debridement and systemic antibiotics; however, adjunctive wound care plays a crucial role in recovery. VELVERT Objective: To assess the safety and efficacy of Velvert antimicrobial dressing as an adjunct to standard care in patients with NSTI. Methods: A single-center, open-label, non-randomized clinical study was conducted at M.L.B. Medical College, Jhansi, enrolling 20 patients (18-70 years) with clinically diagnosed NSTI. After debridement, Velvert dressings were applied every fourth day for up to 60 days. Primary endpoints included complete wound closure and rate of healing. Secondary assessments were ≥50% wound area reduction, pain relief, dressing frequency, microbial load, surgeon satisfaction, and adverse events. Both Intent-to-Treat (n=20) and Per-Protocol (n=18) analyses were performed. The study was registered with CTRI (CTRI/2024/02/063282). Results: Complete wound closure occurred in 61.11% (11/18) of Per-Protocol patients, with an additional 16.67% achieving ≥50% reduction. Mean wound size reduction was 20.73 cm Conclusion: Velvert demonstrated safety and efficacy as an adjunct therapy in NSTI, enhancing wound healing, reducing pain, and offering a promising plant-based alternative to conventional dressings.

Indexed as

adverse eventantimicrobialNSTIVELVERT®wound closure

Identifiers

PMID41908592
PMCPMC13023392

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.