ArticleFrontiers in pediatrics2026
The association between patellar malalignment and Osgood-Schlatter disease in children.
Article in Frontiers in pediatrics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
Objective: The aim of this study was to investigate the association between patellar position [assessed by the Insall-Salvati index (ISI)] and Osgood-Schlatter disease (OSD) in children, and to evaluate the predictive value of ISI and body mass index (BMI) for OSD. Methods: A case-control/cross-sectional study was conducted enrolling 127 children aged 10-16 years between March 2023 and June 2025, including 76 children with OSD (observation group) and 51 healthy children (control group). ISI values were measured radiographically, and data on BMI, visual analog scale score, gender, and recent exercise level were collected. Univariate analysis and multivariate logistic regression were used to analyze associated factors, and the predictive performance of ISI and BMI was evaluated using receiver operating characteristic (ROC) curves. Results: The observation group had significantly higher ISI values, BMI values, and proportion of males compared to the control group (all Conclusion: The ISI value is a strong independent indicator associated with OSD, with an optimal cutoff value of 1.14. The pathogenesis of OSD may involve the combined effects of abnormal biomechanics (high ISI) and mechanical load (high BMI and high exercise level). Early screening of ISI may help identify high-risk individuals for targeted prevention.
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