ReviewNeuropsychiatric disease and treatment2026
Association Between Depression and the Risk of Hyperemesis Gravidarum: A Systematic Review and Meta-Analysis.
Review in Neuropsychiatric disease and treatment, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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5 authors.
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Abstract
Background: Hyperemesis gravidarum (HG) is a severe pregnancy-related condition that may be influenced by maternal psychological factors. This meta-analysis aimed to evaluate the association between maternal depression and the risk of HG and to explore whether this association varies by maternal or study characteristics. Methods: A systematic search was conducted in PubMed, Embase, and Web of Science databases up to May 2, 2025, to identify observational studies examining the association between depression, assessed either prior to or during pregnancy, and HG. Heterogeneity was evaluated using the Cochrane Q test and I Results: Totally, 13 case-control studies involving 95,249 pregnant women were included. Maternal depression was associated with a significantly higher risk of HG (OR: 5.08, 95% CI: 2.71-9.52; p < 0.001; I Conclusion: Maternal depression is associated with the occurrence of HG; however, this association does not imply causation, and depressive symptoms may reflect the psychological impact of this severe condition.
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