Evidence map›Paper›PMID 41908332›Full record

ArticleAnimal cells and systems2026

Enhancer RNA-mediated transcriptional regulation of TDP-43 during early neural lineage specification.

Yeonju Jang, Hyohi Lee, Myunggeun Oh, Jiin Moon, Seung-Jin Kim, Jaeil Han, Jong-Lyul Park, Seung-Kyoon Kim

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Animal cells and systems, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yeonju JangDepartment of Convergent Bioscience and Informatics, and Graduate School of Biological Sciences, Chungnam National University, Daejeon, Republic of Korea.
Hyohi LeeDepartment of Convergent Bioscience and Informatics, and Graduate School of Biological Sciences, Chungnam National University, Daejeon, Republic of Korea.
Myunggeun OhDepartment of Convergent Bioscience and Informatics, and Graduate School of Biological Sciences, Chungnam National University, Daejeon, Republic of Korea.
Jiin MoonDepartment of Convergent Bioscience and Informatics, and Graduate School of Biological Sciences, Chungnam National University, Daejeon, Republic of Korea.
Seung-Jin KimDepartment of Biochemistry, College of Natural Sciences, Kangwon National University, Chuncheon, Republic of Korea.
Jaeil HanDepartment of Microbiology and Molecular Biology, Chungnam National University, Daejeon, Republic of Korea.
Jong-Lyul ParkPersonalized Genomic Medicine Research Center, Korea Research Institute of Bioscience & Biotechnology, Daejeon, Republic of Korea.
Seung-Kyoon KimDepartment of Convergent Bioscience and Informatics, and Graduate School of Biological Sciences, Chungnam National University, Daejeon, Republic of Korea.ORCID https://orcid.org/0000-0001-9776-4047

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

TAR DNA-binding protein 43 (TDP-43) is a DNA- and RNA-binding protein that regulates gene expression by modulating transcription and RNA processing. It plays pivotal roles in neuronal development and function, and its mislocalization and aggregation are major pathological features of several neurodegenerative diseases. However, the regulatory mechanisms that control

Indexed as

embryonic stem cells (ESCs)enhancer RNAs (eRNAs)epigeneticsneural lineage specificationTDP-43

Identifiers

PMID41908332
PMCPMC13023014

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.