Evidence map›Paper›PMID 41908294›Full record

ArticleJournal of oral microbiology2026

Possible association between the microbiota in subgingival and atherosclerotic plaque in a cohort of patients with carotid stenosis.

Susanne Schulz, Sophie Börner, Kerstin Bitter, Henda Gheit, Jumber Partsakhashvili, Jörg Ukkat, Danny Misiak, Stefan Reichert

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of oral microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Susanne SchulzDepartment of Operative Dentistry and Periodontology, Martin Luther University Halle-Wittenberg, Halle, Germany.ORCID https://orcid.org/0000-0003-4541-666X
Sophie BörnerDepartment of Operative Dentistry and Periodontology, Martin Luther University Halle-Wittenberg, Halle, Germany.
Kerstin BitterDepartment of Operative Dentistry and Periodontology, Martin Luther University Halle-Wittenberg, Halle, Germany.
Henda GheitDepartment of Operative Dentistry and Periodontology, Martin Luther University Halle-Wittenberg, Halle, Germany.
Jumber PartsakhashviliDepartment of Visceral, Vascular and Endocrine Surgery, University Hospital Halle (Saale), Martin-Luther-University Halle-Wittenberg, Halle, Germany.
Jörg UkkatDepartment of Visceral, Vascular and Endocrine Surgery, University Hospital Halle (Saale), Martin-Luther-University Halle-Wittenberg, Halle, Germany.
Danny MisiakInstitute of Molecular Medicine, Martin Luther University Halle Wittenberg, Halle, Germany.
Stefan ReichertDepartment of Operative Dentistry and Periodontology, Martin Luther University Halle-Wittenberg, Halle, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Periodontal pathogens have been implicated in systemic diseases, including atherosclerosis. This study investigates the relationship between subgingival and microbial colonization of carotid plaque in patients undergoing carotid endarterectomy (DRKS00021598). Methods: Microbial samples from both subgingival and carotid plaques were collected from 25 hospitalized patients. Preoperative all patients underwent periodontal examination. The microbial composition was assessed using metagenomics sequencing of 16S rRNA gene (V3/V4 regions). Results: Bacterial DNA was detected in both subgingival and carotid plaque samples. The microbial composition differed between both communities. Alpha diversity was significantly higher in subgingival samples than in carotid plaques ( Conclusions: These findings show that carotid plaque microbiota differ from subgingival communities and are not exclusively of oral origin, suggesting additional systemic sources.

Indexed as

16S rRNA analysisCarotid artery stenosisinteractionsperiodontitissubgingival microbiota

Identifiers

PMID41908294
PMCPMC13023004

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.