Evidence map›Paper›PMID 41908292›Full record

ArticleJournal of oral microbiology2026

Oral-heart axis from pregnancy and postpartum: maternal oral microbiota relates with cardiac reverse remodeling.

Juliana Morais, Maria João Azevedo, Ana Filipa Ferreira, Bernd W Brandt, Egija Zaura, Mark J Buijs, Adelino F Leite-Moreira, Carla Ramalho, António Barros, Inês Falcão Pires and 1 more

Abstract read
In one paragraph

Article in Journal of oral microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Juliana MoraisRISE-Health, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina, Universidade do Porto, Porto, Portugal.ORCID https://orcid.org/0000-0003-3783-6074
Maria João AzevedoDepartment of Preventive Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0002-9117-4684
Ana Filipa FerreiraRISE-Health, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina, Universidade do Porto, Porto, Portugal.ORCID https://orcid.org/0000-0003-2080-309X
Bernd W BrandtDepartment of Preventive Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0002-1155-1989
Egija ZauraDepartment of Preventive Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0003-1432-6194
Mark J BuijsDepartment of Preventive Dentistry, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0002-4972-9797
Adelino F Leite-MoreiraRISE-Health, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina, Universidade do Porto, Porto, Portugal.ORCID https://orcid.org/0000-0001-7808-3596
Carla RamalhoDepartamento de Obstetrícia, Unidade Local de Saúde de São João, Porto, Portugal.ORCID https://orcid.org/0000-0002-3977-3946
António BarrosRISE-Health, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina, Universidade do Porto, Porto, Portugal.ORCID https://orcid.org/0000-0002-9103-5852
Inês Falcão PiresRISE-Health, Departamento de Cirurgia e Fisiologia, Faculdade de Medicina, Universidade do Porto, Porto, Portugal.
Benedita Sampaio-Maiai3S - Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal.ORCID https://orcid.org/0000-0001-9368-8075

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Emerging evidence links the oral microbiota to cardiovascular health, but this relationship remains poorly understood during pregnancy. Here, we investigated associations between the oral microbiota, cardiovascular physiology, and diet during and after pregnancy. Materials and methods: Salivary microbiota from 65 women in the 3rd trimester and 6 months postpartum were analyzed by 16S rRNA gene sequencing. Cardiovascular function was assessed via echocardiography, endothelial function by EndoPAT Results: Left ventricular end-diastolic volume (LVEDV) was negatively associated with nitrite-reducing bacteria, namely, Conclusion: In conclusion, the salivary microbiota profile was associated with cardiovascular physiology during pregnancy and with postpartum cardiovascular recovery. These findings warrant confirmation in larger cohorts to clarify their clinical relevance.

Indexed as

cardiovascular functionendothelial functionoral-heart axisPregnancysalivary microbiota

Identifiers

PMID41908292
PMCPMC13021013

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.