Evidence map›Paper›PMID 41908010›Full record

ArticleBioinformation2025

Diagnostic utility of ADA and CBNAAT in tubercular pleural effusion.

N Patel Ronak Kumar, Rahul Soni, Darshi Rastogi, Pankaj Kumar Gupta, Sachin Parmar

Abstract read
In one paragraph

Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

N Patel Ronak KumarDepartment of Pulmonary Medicine, L.N Medical College & J.K Hospital, Bhopal, Madhya Pradesh, India.
Rahul SoniDepartment of Pulmonary Medicine, Birsa Munda Government Medical College, Shahdol, Madhya Pradesh, India.
Darshi RastogiDepartment of Pulmonary Medicine, L.N Medical College & J.K Hospital, Bhopal, Madhya Pradesh, India.
Pankaj Kumar GuptaDepartment of General Medicine, Birsa Munda Government Medical College Shahdol, Madhya Pradesh, India.
Sachin ParmarDepartment of Community Medicine, V.K.S. Government Medical College, Neemuch, Madhya Pradesh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diagnostic performance of Adenosine Deaminase (ADA) and Cartridge-Based Nucleic Acid Amplification Test (CBNAAT) in diagnosing tubercular pleural effusion (TPE) is of interest. Hence, a study was conducted over 18 months at LN Medical College and JK Hospital, Bhopal. The study involved 108 adult patients with TPE. Data shows that CBNAAT, although highly specific, had limited sensitivity, while ADA ≥40 IU/L demonstrated strong sensitivity. ADA levels were significantly higher in CBNAAT-positive participants, suggesting that combining both tests enhances diagnostic accuracy. This approach can help reduce the need for invasive procedures and improve timely treatment, especially in resource-limited settings. We show the importance of using ADA and CBNAAT together in the diagnosis of TPE.

Indexed as

Adenosine Deaminase (ADA)CBNAATdiagnostic accuracysensitivityTubercular pleural effusion

Identifiers

PMID41908010
PMCPMC13018321

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.