Evidence map›Paper›PMID 41907978›Full record

ArticleBioinformation2025

D-dimer levels in acute exacerbation of asthma among children: A correlation study.

Pragya Pragya, Prateek Pandey, Ankita Dinkar, Fahad Naaz, Ashutosh Kumar, Partha Kumar Chaudhuri

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Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Pragya PragyaDepartment of Paediatrics, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
Prateek PandeyDepartment of Paediatrics, Sheikh Bhikhari Medical College and Hospital, Hazaribagh, Jharkhand, India.
Ankita DinkarDepartment of Paediatrics, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
Fahad NaazDepartment of Paediatrics, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
Ashutosh KumarDepartment of Paediatrics, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.
Partha Kumar ChaudhuriDepartment of Paediatrics, Rajendra Institute of Medical Sciences, Ranchi, Jharkhand, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Asthma exacerbations in children may involve systemic coagulation changes reflected by elevated D-dimer levels. Therefore, it is of interest to evaluate 50 children aged 2-15 years to assess the correlation between D-dimer levels and acute exacerbation severity. D-dimer positivity increased significantly with severity-from 9.5% (mild) to 45.5% (moderate) and 71.4% (severe) (p=0.004). Positive D-dimer results were also strongly associated with longer hospital stays (p<0.001). Thus, we show that D-dimer is a valuable biomarker for assessing exacerbation severity and predicting clinical outcomes in pediatric asthma.

Indexed as

asthma exacerbationbiomarkerchildrencoagulation abnormalitiesD-dimerpulmonary score

Identifiers

PMID41907978
PMCPMC13018340

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