ArticleBioinformation2025
Immediate implant placement with and without platelet-rich fibrin and decalcified freeze-dried bone graft.
Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
There is a high risk of vertical and horizontal bone resorption in the peri-implant gap following immediate implant placement after non-molar tooth extraction, which compromises implant stability, hard/soft tissue preservation, and esthetic outcomes. The present study was a randomized controlled clinical trial included 40 patients requiring a single non-molar tooth extraction and immediate implant placement. Patients were randomly allocated into two equal groups (n=20). In the Test group, the peri-implant gap was filled with a composite of PRF and DFDBA. In the Control group, no grafting material was placed. The primary outcome was vertical bone level (VBL) change at 6 months, measured on standardized radiographs. Secondary outcomes included horizontal bone thickness changes measured on CBCT, implant stability quotient (ISQ) at baseline and 3 months and Pink Esthetic Score (PES) at 6 months. Independent t-tests were used for statistical analysis (α=0.05). The adjunctive use of a composite PRF and DFDBA graft in immediate implant placement sockets significantly improves the preservation of peri-implant hard and soft tissues, enhances secondary implant stability and leads to superior esthetic outcomes compared to no grafting.
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