Evidence map›Paper›PMID 41907941›Full record

ArticleBioinformation2025

Salivary and serum alkaline phosphatase as biomarkers in type 2 diabetes mellitus: Association with periodontal health and disease.

Kinjal Desai, Bela Dave, Tanya Nagrani, Reena Chaudhary, Avani Patel, Shalini Gohil

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Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Kinjal DesaiDepartment of Periodontology, Gujarat University, Ahmedabad, India.
Bela DaveDepartment of Periodontology, AMC Dental College and Hospital, Khokhara, Ahmedabad, Gujarat, India.
Tanya NagraniDepartment of periodontology & Implantology, Siddhpur Dental College and Hospital, Siddhpur, Gujarat, India.
Reena ChaudharyDepartment of Oral & Maxillofacial Pathology, Siddhpur Dental College and Hospital, Siddhpur - 384151 Gujarat, India.
Avani PatelDepartment of Oral & Maxillofacial Pathology and Oral Microbiology, Narsinhbhai Patel Dental College and Hospital, Visnagar Sankalchand Patel University, Visnagar, Gujarat, India.
Shalini GohilDepartment of Periodontology, Founder and chief dentist at Family Dental Clinic, Olpad, Surat, Surat - 395007, Gujarat, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic periodontitis in patients with type 2 diabetes mellitus (T2DM) requires reliable biomarkers for early detection and monitoring. Therefore, it is of interest to evaluate serum and salivary alkaline phosphatase (ALP) levels in 90 participants divided into healthy controls, diabetics with healthy periodontium and diabetics with chronic periodontitis. Salivary and serum ALP levels increased progressively across the groups and were significantly highest in diabetics with periodontitis (p < 0.001). Strong correlations were observed between salivary ALP, serum ALP and periodontal parameters such as probing depth and clinical attachment loss. Salivary ALP shows strong potential as a non-invasive biomarker for periodontal tissue destruction in diabetic patients.

Indexed as

Alkaline phosphatasebiomarkerchronic periodontitisperiodontal diseasesalivatype-2 diabetes mellitus

Identifiers

PMID41907941
PMCPMC13018452

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