ArticleBioinformation2025
New frontiers in oral submucous fibrosis: The promise of collagen based interventions.
Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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0 citing papers in PubMed.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oral Sub-mucous Fibrosis (OSMF) is a chronic, progressive and potentially malignant disorder characterized by inflammation and fibrosis of the oral mucosa, often leading to significant morbidity and impaired quality of life. The pathogenesis of OSMF is strongly associated with abnormal collagen metabolism, resulting in excessive deposition and reduced degradation of collagen fibres. Traditional therapeutic modalities have shown limited success in reversing the fibrotic changes, underscoring the need for novel treatment approaches. Therefore, it is of interest to explore the emerging role of collagen-based interventions including modulation therapies, enzymatic degradation, and regenerative techniques) which target key molecular pathways to improve functional outcomes and arrest disease progression. The potential of combining collagen- based approaches with regenerative and personalized medicine in the effective management of OSMF is also promising.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.