Evidence map›Paper›PMID 41907876›Full record

ArticleBioinformation2025

Impact of gut microbiota on human immune system development: A longitudinal study.

Dipalben Shreyaskumar Patel, Mukul Singh, Vivekanand Ashok, Amrit Podder, Jorge Antonio Segovia Guerrero, Renato Matías Torres Montano, Abhishek Kumar Semwal, Luis Patricio Dávila Aguilar, Karina Vanessa Herrera Riofrío

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Article in Bioinformation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Dipalben Shreyaskumar PatelDepartment of Obstetrics and Gynecology, Akshaydeep Hospital, Gujarat, India.
Mukul SinghDepartment of General Surgery, All India Institute of Medical Sciences (AIIMS), Gorakhpur, Uttar Pradesh, India.
Vivekanand AshokDepartment of ENT - Head and Neck Surgery, Azeezia Health City, Palakkad, Kerala, India.
Amrit PodderDepartment of Physiology, Teerthanker Mahaveer Medical College & Research Centre, Teerthanker Mahaveer University, Moradabad, Uttar Pradesh, India.
Jorge Antonio Segovia GuerreroDepartment of Emergency, Armed Forces Specialty Hospital No. 1, Quito, Ecuador.
Renato Matías Torres MontanoTeaching Analyst, Armed Forces Specialty Hospital No. 1, Quito, Ecuador.
Abhishek Kumar SemwalKayachikitsa, Ankerite Ayurvedic Medical College and Hospital, Lucknow, India.
Luis Patricio Dávila AguilarLuis Patricio Dávila Aguilar, Internal Medicine Physician - Hematology, Armed Forces Specialties Hospital No. 1, Quito, Ecuador.
Karina Vanessa Herrera RiofríoDepartment of Nutrition and Dietetics Specialty, Leader of the Nutrition and Dietetics Specialty at HE-1, Armed Forces Specialty Hospital No. 1, Quito, Ecuador.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of the immune system in early childhood is influenced by various factors, and the role of gut microbiota in this process remains a critical area of investigation. Therefore, it is of interest to investigate the impact of gut microbiota on immune system development in 110 children over three years. It found significant correlations between microbiota diversity and immune markers, with higher diversity linked to improved immune regulation. The study also highlighted the negative effects of early antibiotic use and the positive influence of a fiber-rich diet on gut microbiota composition and immune function. Thus, we show the critical role of early- life microbial exposures in shaping immune health.

Indexed as

Antibiotic usediversityguts microbiotaimmune markerslongitudinal study

Identifiers

PMID41907876
PMCPMC13018343

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