ArticleFrontiers in surgery2026
The structural and microbiological properties of human cadaveric iliac vessel grafts stored at a readily available standard freezer: a comprehensive analysis as a function of storage time.
Article in Frontiers in surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Vascular allografts are very important tool for transplantation procedures especially in living donor liver transplantation (LT). The aim of this study is to evaluate the histopathological and microbiological properties of human cadaveric iliac vessel grafts stored by a readily available method (freezing at -24 °C without using cryoprotectant solution) and to determine the impact of storage time on these parameters. Methods: Donor characteristics, histopathological changes on light microscopy [tunica intima, internal elastic lamina (IEL), tunica media in artery allografts], scanning electron microscopy (SEM) endothelial morphology grade and the microbiological results were recorded. Results: A total of 54 cadaveric iliac vessel grafts (28 iliac arteries and 26 iliac veins) harvested from 28 donors were grouped based on the storage period as fresh control (0-24 h, Conclusions: In conclusion, our findings revealed that iliac vessel allografts stored for less than 12 months had the lower risk of morphological, structural and degenerative endothelial changes. Hence, this simple and readily available low cost storage method seems to offer a favorable alternative in allograft storage up to 12 months.
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