Evidence map›Paper›PMID 41907710›Full record

ArticleGut microbes reports2024

Quantitative Distribution Profile of Cadmium and Lead in Different Organs of Rats and Mitigation of their Accumulation Through Probiotic Treatment.

Omprakash Omprakash, Rohit Kumar, Prashant Singh, Poonam Devi, Anuj Malik, Nitin Mahal

Abstract read
In one paragraph

Article in Gut microbes reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Omprakash OmprakashICAR-National Dairy Research Institute, Animal Biochemistry Division, Karnal, India.
Rohit KumarCollege of Public Health and Human Sciences, Oregon State University, Corvallis, OR, USA.
Prashant SinghICAR-National Dairy Research Institute, Animal Biochemistry Division, Karnal, India.
Poonam DeviICAR-National Dairy Research Institute, Animal Biochemistry Division, Karnal, India.
Anuj MalikICAR-National Dairy Research Institute, Animal Biochemistry Division, Karnal, India.
Nitin MahalICAR-National Dairy Research Institute, Animal Biochemistry Division, Karnal, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cadmium (Cd) and lead (Pb) are toxic heavy metals that can have severe adverse effect on human health and environment. Pb contamination remains a significant concern due to its persistence in the environment, while Cd primarily enters the environment through mining, contaminating water and soil. These metals have a propensity to accumulate within various organs by displacing the essential divalent cation Ca2+, which plays a crucial role in mammalian physiology. However, the pattern of accumulation is not uniform across different organs and can vary due to distinct processing mechanisms and affinities exhibited by heavy metals toward various organ systems. This present study aims to comprehensively assess the quantitative distribution of cadmium and lead within the organs of Wistar rats, who were administered 50 mg and 100 mg per kilogram of body weight, respectively, of Cd and Pb. Furthermore, the study employs a therapeutic and interventional approach to mitigate heavy metal toxicity by introducing two probiotic strains:

Indexed as

antioxidant enzymesCadmiumleadprobioticsWistar rat

Identifiers

PMID41907710
PMCPMC12940153

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.