Evidence map›Paper›PMID 41907709›Full record

ArticleGut microbes reports2024

Bimodal distribution of intestinal

Khemlal Nirmalkar, Jigar Patel, Dae-Wook Kang, Andrew Bellinghiere, Devin A Bowes, Fatir Qureshi, James B Adams, Rosa Krajmalnik-Brown

Abstract read
In one paragraph

Article in Gut microbes reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Review
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Khemlal NirmalkarBiodesign Center for Health Through Microbiomes, Arizona State University, Tempe, AZ, USA.ORCID https://orcid.org/0000-0001-6732-9175
Jigar PatelBiodesign Center for Health Through Microbiomes, Arizona State University, Tempe, AZ, USA.
Dae-Wook KangBiodesign Center for Health Through Microbiomes, Arizona State University, Tempe, AZ, USA.
Andrew BellinghiereBiodesign Center for Health Through Microbiomes, Arizona State University, Tempe, AZ, USA.
Devin A BowesBiodesign Center for Health Through Microbiomes, Arizona State University, Tempe, AZ, USA.
Fatir QureshiWhitehead Institute for Biomedical Research, Cambridge, MA, USA.
James B AdamsBiodesign Center for Health Through Microbiomes, Arizona State University, Tempe, AZ, USA.
Rosa Krajmalnik-BrownBiodesign Center for Health Through Microbiomes, Arizona State University, Tempe, AZ, USA.ORCID https://orcid.org/0000-0001-6064-3524

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gastrointestinal (GI) tract harbors a complex and remarkably diverse microbial ecosystem that profoundly impacts various aspects of health and pathophysiology. While bacteria overwhelmingly represent most of the GI microbiota, it is imperative to consider the presence and function of fungal constituents (i.e. mycobiota) within the GI ecosystem. The substantial incidence of GI disorders and associated manifestations in children diagnosed with autism spectrum disorder (ASD) suggests a plausible contributory role of the gut mycobiota. This work aimed to elucidate the gut mycobiota in a cohort of 38 typically developing children (TD) and 40 children with ASD. Fecal samples were collected from all participants, autism severity and GI symptoms were assessed to unravel the potential implications of mycobiota alterations in the gut. We performed fungal internal transcribed spacer (ITS) gene amplicon sequencing to analyze the fungal composition and investigate their relationship with GI and autism symptoms. Among gut mycobiota,

Indexed as

Autism spectrum disorder (ASD)candida albicansfungal microbiotainternal transcribed spacer (ITS) sequencingmycobiota

Identifiers

PMID41907709
PMCPMC12940154

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.