Evidence map›Paper›PMID 41907665›Full record

ReviewSafety and health at work2026

Occupational Benzene Exposure and Hepatobiliary and Pancreatic Cancers: A Systematic Review and Meta-analysis.

Michele Sassano, Monireh S Seyyedsalehi, Paolo Boffetta

Abstract readReview
In one paragraph

Review in Safety and health at work, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michele SassanoDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
Monireh S SeyyedsalehiDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.
Paolo BoffettaDepartment of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evidence on the association between benzene and hepatobiliary and pancreatic cancers is scarce. Hence, we aimed to summarize current literature on the association between occupational benzene exposure and these cancers. We conducted a systematic review and meta-analysis by searching Pubmed, Embase, and Scopus through April 2024 to identify cohort and nested case-control studies. We evaluated study quality with the Newcastle-Ottawa Scale and estimated pooled relative risks (RRs) and 95% confidence intervals (CIs) using Paule-Mandel method. Twenty-nine studies were included in the meta-analysis. Occupational benzene exposure was associated with hepatobiliary cancer incidence (RR: 1.14; 95% CI: 1.04-1.24; I

Indexed as

benzenegallbladder cancerliver cancermeta-analysispancreatic cancer

Identifiers

PMID41907665
PMCPMC13023073

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.