Evidence map›Paper›PMID 41907646›Full record

ArticleFrontiers in oncology2026

Regular nutritional monitoring in pediatric cancer patients undergoing radiotherapy: a prospective observational pilot study.

Dilek Gül, Feyzanur Ekşi Özdaş, Nurşah Eker, Zerrin Özgen, Engin Tutar, Beste Melek Atasoy

Abstract read
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Article in Frontiers in oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Dilek GülRadiation Oncology Clinic, Marmara University Pendik Education and Research Hospital, Istanbul, Türkiye.
Feyzanur Ekşi ÖzdaşDepartment of Nutrition and Dietetics, Marmara University Pendik Education and Research Hospital, Istanbul, Türkiye.
Nurşah EkerDepartment of Pediatrics, Division of Oncology and Hematology, Marmara University School of Medicine, Istanbul, Türkiye.
Zerrin ÖzgenDepartment of Radiation Oncology, Marmara University School of Medicine, Istanbul, Türkiye.
Engin TutarDepartment of Pediatrics, Division of Gastroenterology, Marmara University School of Medicine, Istanbul, Türkiye.
Beste Melek AtasoyDepartment of Radiation Oncology, Marmara University School of Medicine, Istanbul, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This pilot study aimed to explore the possible effects of regular, ongoing nutritional monitoring on dietary status, treatment results, and quality of life in pediatric cancer patients receiving radiotherapy. The study also sought to assess the potential role of caregiver nutritional support during treatment. Materials and methods: Anthropometric measures, including weight, height, body mass index z-score (BMI), and mid-upper arm circumference (MUAC), were recorded for 15 patients. Individual nutritional plans, the quality of caregiver-provided nutritional support, and inflammatory parameters were assessed weekly during radiotherapy. Quality of life was measured using a validated questionnaire at the beginning and end of radiotherapy. Results: More than one-third of patients were malnourished prior to radiotherapy. A decline was observed, especially in the fourth week of radiotherapy, for weight (p = 0.016), BMI (p = 0.013), and MUAC (p = 0.081). The albumin-to-globulin ratio (AGR) (p = 0.004) and platelet-lymphocyte ratio (PLR) (p = 0.013) peaked at the same time. Caregiver nutritional support scores (p = 0.026) and quality-of-life scores (p = 0.037) were lower in patients who experienced weight loss during radiotherapy. The median follow-up period was 13 months (range 9-16 months). Progression-free survival showed a non-significant trend in patients without weight loss [85.7% (95% CI, 42-99%) vs. 70% (95% CI, 35-93%), p = 0.590] and was significantly better in patients who began radiotherapy without malnutrition [100% (95% CI, 66-100%) vs. 50% (95% CI, 12-88%), p = 0.019]. Conclusion: Our initial findings suggest that regular nutritional monitoring may be a part of treatment plans, not just supportive care, for pediatric patients undergoing radiotherapy. Further research involving larger patient populations should be conducted to establish high-quality evidence on this topic.

Indexed as

caregiver support qualityclinical outcomenutritional monitoringpediatric cancerquality of liferadiotherapy

Identifiers

PMID41907646
PMCPMC13017324

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.