ReviewFrontiers in endocrinology2026
Impaired awareness of hypoglycemia: can structured education address this persistent challenge?
Review in Frontiers in endocrinology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Impaired Awareness of Hypoglycemia (IAH) describes a condition in insulin-treated diabetic patients characterized by a diminished ability to perceive the onset of acute hypoglycemia. With an estimated prevalence ranging from 23.2% to 26.3%, IAH is associated with a significantly elevated risk of severe hypoglycemia (SH) and is increasingly linked to emotional disturbances. As a major challenge in diabetes management, the primary interventions for IAH include structured education and diabetes technology. However, the real-world impact of diabetes technology on the frequency of SH and IAH remains contentious. While structured education is fundamental for addressing IAH, its implementation is often inadequate, and program content requires optimization, thereby limiting the effectiveness of current educational approaches. Consequently, there is a persistent need for enhanced treatment strategies. With advancements in intelligent technology, a hybrid model integrating structured education with diabetes technology is emerging as a promising trend. Furthermore, IAH can contribute to cognitive dysfunction, which in turn impairs the ability to perceive and respond to hypoglycemic events. This suggests that incorporating cognitive interventions into structured education may represent a novel therapeutic avenue and potentially yield innovative management solutions.
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