Evidence map›Paper›PMID 41907493›Full record

ArticleJournal of pain research2026

Association Between Pain Subtypes and Cognitive Impairment in Parkinson's Disease.

Liang Gao, Zhichang Li, Laisheng Cai, Wenyuan Xu, Yi Liu

Abstract read
In one paragraph

Article in Journal of pain research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Liang GaoDepartment of Neurology, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Zhichang LiDepartment of Neurology, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Laisheng CaiDepartment of Neurology, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People's Republic of China.ORCID 0000-0002-4513-7911
Wenyuan XuDepartment of Neurology, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People's Republic of China.
Yi LiuDepartment of Neurology, the First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the impact of different pain subtypes on cognitive function in patients with Parkinson's disease (PD). Patients and Methods: A total of 344 patients with PD were enrolled in this cross-sectional study, comprising 187 males (54.4%) and 157 females (45.6%), with ages ranging from 32 to 84 years old. Demographic and clinical data were collected, including age, disease duration, levodopa equivalent daily dose (LEDD), and scores on the Unified Parkinson's Disease Rating Scale part III (UPDRS-III), Hoehn and Yahr (H&Y) scale, Pittsburgh Sleep Quality Index (PSQI), King's Parkinson's Disease Pain Scale (KPPS), Visual Analogue Scale (VAS), Mini-Mental State Examination (MMSE), Activities of Daily Living (ADL) scale, Hamilton Depression Rating Scale (HAMD), and Hamilton Anxiety Rating Scale (HAMA). Results: Cognitive impairment was present in 56.4% of patients with PD. Compared with those with normal cognition, patients with cognitive impairment were older, had a later age at onset, more severe motor symptoms, higher levels of anxiety and depression, and greater pain severity. Specifically, they reported more chronic pain, central pain, visceral pain, "off" period dystonia, discoloration/swelling, and generalized lower abdominal pain ( Conclusion: Cognitive impairment in PD is closely associated with pain severity, with certain pain subtypes exerting a stronger influence on cognition.

Indexed as

cognitive impairmentking’s parkinson’s disease pain scalemini-mental state examinationpainparkinson’s disease

Identifiers

PMID41907493
PMCPMC13024347

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.