Genomic insights into the diversity, antibiotic resistance, and virulence potential of staphylococci isolated from pediatric patients with chronic otitis media with effusion (COME).

Jonald Low, Haohong Tu, Mohamed Elbadawey, Ali Wayes, Nicholas Jakubovics, Siew Woh Choo, Wee Wei Yee

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Article in PeerJ, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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7 authors.

Jonald Low *School of Science, Monash University Malaysia, Selangor, Malaysia.

Haohong Tu *Department of Biology, Wenzhou-Kean University, Zhejiang, China.

Mohamed ElbadaweyTanta University, Gharbia Governorate, Egypt.

Ali WayesKirkuk University, Kirkuk, Iraq.

Nicholas JakubovicsNewcastle University, Newcastle upon Tyne, United Kingdom.

Siew Woh ChooDepartment of Biology, Wenzhou-Kean University, Zhejiang, China.

Wee Wei YeeSchool of Science, Monash University Malaysia, Selangor, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic otitis media with effusion (COME) is a prevalent pediatric condition characterized by persistent middle ear effusion, potentially leading to hearing loss and developmental delays. Methods: We investigated the diversity, antibiotic resistance, and virulence potential of Results: Phylogenetic analysis revealed three coagulase positive Conclusion: Our genomic analysis shows that COME-associated

Indexed as

Drug Resistance, BacterialOtitis Media with EffusionStaphylococcal InfectionsStaphylococcusAnti-Bacterial AgentsChildChild, PreschoolChronic DiseaseFemaleGenetic VariationGenome, BacterialGenomicsHumansMicrobial Sensitivity TestsMultilocus Sequence TypingPhylogenyAnti-Bacterial AgentsRNA, Ribosomal, 16SVirulence FactorsAntibiotic resistanceChronic otitis media with effusionCoagulase negative StaphylococcusCoagulase positive StaphylococcusHorizontal gene transferVirulence factor

Identifiers

PMID41907467

DOI10.7717/peerj.20782

PMCPMC13024242

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