Evidence map›Paper›PMID 41907372›Full record

ReviewInternational journal of nanomedicine2026

Antimicrobial Hydrogel for Diabetic Wound Treatment.

Huan Huang, Puhua Zhang, Songjie Li, Qiuhe Song, Zhongcheng Hu, Chunxia Zhou, Lei Yang

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Huan Huang *Department of Dermatology, Affiliated Hospital of Jiujiang University, Jiujiang, 332000, People's Republic of China.
Puhua Zhang *Graduate Department, Gannan Medical University, Ganzhou, 341000, People's Republic of China.
Songjie LiDepartment of Plastic and Reconstructive Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, 710032, People's Republic of China.
Qiuhe SongDepartment of Dermatology, Affiliated Hospital of Jiujiang University, Jiujiang, 332000, People's Republic of China.
Zhongcheng HuDepartment of Dermatology, Affiliated Hospital of Jiujiang University, Jiujiang, 332000, People's Republic of China.
Chunxia ZhouDepartment of Dermatology, Affiliated Hospital of Jiujiang University, Jiujiang, 332000, People's Republic of China.
Lei YangZhejiang Provincial Key Laboratory of Silk and Silk Protein New Materials, Zhejiang Academy of Agricultural Sciences, Hangzhou, 310021, People's Republic of China.ORCID 0000-0001-8859-9692

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic wound infections pose a significant clinical challenge. Chronic wounds associated with diabetes mellitus exhibit delayed healing and, if not managed appropriately, are highly susceptible to infections that may lead to life-threatening complications in severe cases. Antimicrobial hydrogels have become promising materials for diabetic wound management due to their moisture retention, biocompatibility, biodegradability, and intrinsic antimicrobial properties. As wound dressings, they offer advantages such as wound exudate absorption, controlled drug 2release, and minimized toxic side effects. By incorporating antimicrobial components (e.g. chitosan (CS), polyethylenimine (PEI)) or serving as carriers for antimicrobial agents (e.g. antibiotics, antimicrobial peptides (AMPs), inorganic metal materials, and carbon nanomaterials (CNMs)), antimicrobial hydrogels effectively inhibit microbial growth. With ongoing research, the development of intelligent, multifunctional, and highly responsive antimicrobial hydrogels continues to advance, offering more precise and rapid therapeutic solutions for diabetic wounds. This review first examines the impact of infection on diabetic wound healing, followed by an overview of the definition and classification of hydrogels. Subsequently, various antimicrobial hydrogels and their mechanisms of action are summarized, along with an exploration of their fabrication methods. By analyzing recent advancements in antimicrobial hydrogel research, this review aims to provide insights into future research directions and potential clinical applications for diabetic wound management.

Indexed as

Anti-Infective AgentsDiabetes ComplicationsHydrogelsWound HealingWound InfectionAnimalsBandagesHumansAnti-Infective AgentsHydrogelsantimicrobial hydrogeldiabetic woundhydrogelwound healing

Identifiers

PMID41907372
PMCPMC13024488

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.