Evidence map›Paper›PMID 41907288›Full record

ArticleFrontiers in medicine2026

Real-world effectiveness of MiSight 1 Day contact lenses in Taiwanese children: a multicenter retrospective study.

Yu-Te Huang, I-Ming Wang, Yu-Hsuan Huang, Pi-Jung Lin, Hao-Lin Su, Tzu-Hsun Tsai, Yao-Lin Liu, I-Jong Wang, Hui-Ju Lin

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Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Yu-Te Huang *Graduate Institute of Biomedical Sciences, China Medical University, Taichung, Taiwan.
I-Ming Wang *Department of Medical Research, China Medical University, Taichung, Taiwan.
Yu-Hsuan HuangShilin Universal Eye Center, Taipei, Taiwan.
Pi-Jung LinUniversal Eye Center, Taichung, Taiwan.
Hao-Lin SuUniversal Eye Center, Taichung, Taiwan.
Tzu-Hsun TsaiDepartment of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
Yao-Lin LiuDepartment of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
I-Jong WangDepartment of Ophthalmology, National Taiwan University Hospital, Taipei, Taiwan.
Hui-Ju LinEye Center, China Medical University Hospital, Taichung, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To evaluate the real-world effectiveness of MiSight 1 Day soft contact lenses for myopia control in Taiwanese children using age-, sex-, and percentile-matched axial length (AL) references. Methods: Retrospective multicenter study across 23 Universal Eye Center clinics. Children aged 6-18 years who initiated MiSight between October 2020 and July 2022 and completed ≥12 months of follow-up were included. Spherical equivalent (SE) and AL were extracted from clinical records and annualized. Observed AL change was compared with matched Taiwanese normative percentiles to estimate axial suppression. Subgroups included age, baseline AL percentile, and prior treatment history. Results: A total of 368 eyes from 368 patients were analyzed (mean age 11.8 ± 2.3 years; 52% female; mean follow-up 19.2 ± 5.0 months). Mean SE progression was -0.41 ± 0.42 D/year. Mean AL elongation was 0.17 mm/year, corresponding to a mean AL suppression of 0.06 mm/year relative to matched Taiwanese norms. Visual performance was favorable, with 98% achieving ≥20/25. Outcomes were similar across prior treatment groups, including previous atropine or orthokeratology exposure. Conclusion: In routine Taiwanese practice, MiSight 1 Day provided meaningful myopia control and maintained good vision. AL growth was reduced by 27% versus matched normative expectations. These findings support the translational effectiveness of MiSight and emphasize the value of regional normative benchmarks for clinical interpretation.

Indexed as

axial lengthMiSight 1 Daymyopia controlpercentile-matched normsreal-world study

Identifiers

PMID41907288
PMCPMC13021410

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.