Evidence map›Paper›PMID 41907280›Full record

ArticleFrontiers in medicine2026

Artificial intelligence-based endoscopic ultrasonography model for detecting the origin layer of gastric subepithelial lesions.

Xiao Wang, Liangpeng Pu, Shanshan Yan, Shuaishuai Zhuang, Jie Hua, Xiaopu He

Abstract read
In one paragraph

Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Xiao WangDepartment of Geriatric Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Liangpeng PuDepartment of Geriatric Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Shanshan YanDepartment of Geriatric Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Shuaishuai ZhuangDepartment of Geriatric Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Jie HuaDepartment of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Xiaopu HeDepartment of Geriatric Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Gastric subepithelial lesions (SELs) are typically covered by intact mucosa, which challenges the determination of their layer of origin under conventional endoscopy. Endoscopic ultrasonography (EUS) is indispensable for diagnosing SELs. However, EUS operation and interpretation are more challenging than standard endoscopy and are subject to inter-observer variability. This study aimed to develop a novel AI system based on the MedMamba architecture to assist clinicians in identifying the layer of origin of gastric SELs. Methods: We retrospectively collected data from patients who underwent EUS at the First Affiliated Hospital of Nanjing Medical University between May 1, 2016 and May 1, 2023. The dataset comprised 1,855 images from 320 patients. Images were split into training, validation, and test sets at an 8:1:1 ratio at the patient level to prevent data leakage. A structured State space sequence model (MedMamba) was trained and the performance was compared against endoscopists. Results: The proposed MedMamba model achieved an overall accuracy of 92.04% (95%CI: 90.33-93.75%), with 94.83% (95%CI: 93.22-96.44%) specificity and 81.11% (95%CI: 75.19-87.03%) sensitivity in the five-category classification. It achieved high sensitivity and accuracy, outperforming other AI models. Conclusion: The MedMamba-based AI system demonstrated superior performance in discriminating the layer of origin of SELs compared with other AI models, indicating its potential utility in reducing diagnostic variability and enhancing clinical diagnostic workflows.

Indexed as

artificial intelligencedeep learningendoscopic ultrasonographygastric subepithelial lesionsMedMamba

Identifiers

PMID41907280
PMCPMC13017373

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.