ReviewJournal of inflammation research2026
Diagnosis and Management of Comorbid Autoimmune Disorders in Children with Chronic Spontaneous Urticaria.
Review in Journal of inflammation research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
Chronic urticaria (CU) is characterized by the recurrent occurrence of wheals and/or angioedema for more than six weeks. CU comprises two principal subtypes: chronic spontaneous urticaria (CSU) and chronic inducible urticaria (CIndU). Increasing evidence suggests that CSU has an autoimmune basis, and patients with CSU exhibit a higher prevalence of concomitant autoimmune disorders. While this association has been well documented in adults, data in pediatric populations remain limited. Available studies indicate that the overall burden of autoimmunity in children with CSU may be lower than in adults; however, several autoimmune diseases-including autoimmune thyroid disease, celiac disease, type 1 diabetes mellitus, vitiligo, systemic lupus erythematosus, and juvenile idiopathic arthritis-have been reported with increased frequency in pediatric CSU cohorts. A clearer understanding of these associations is important for guiding clinical evaluation and management. This review summarizes current evidence on the epidemiology and risk factors for autoimmune comorbidities in pediatric CU and discusses practical considerations for screening and management in affected children.
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